These authors contributed equally to this work.
Cover Picture: Light-Regulated Stapled Peptides to Inhibit Protein–Protein Interactions Involved in Clathrin-Mediated Endocytosis (Angew. Chem. Int. Ed. 30/2013)
Article first published online: 1 JUL 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 52, Issue 30, page 7607, July 22, 2013
How to Cite
Nevola, L., Martín-Quirós, A., Eckelt, K., Camarero, N., Tosi, S., Llobet, A., Giralt, E. and Gorostiza, P. (2013), Cover Picture: Light-Regulated Stapled Peptides to Inhibit Protein–Protein Interactions Involved in Clathrin-Mediated Endocytosis (Angew. Chem. Int. Ed. 30/2013). Angew. Chem. Int. Ed., 52: 7607. doi: 10.1002/anie.201304975
- Issue published online: 17 JUL 2013
- Article first published online: 1 JUL 2013
- clathrin-mediated endocytosis;
- protein–protein interactions
Remote control of membrane traffic is described by E. Giralt, P. Gorostiza, et al. in their Communication on page 7704 ff. Photoswitchable inhibitors of protein–protein interactions have been applied to photoregulate clathrin-mediated endocytosis in living cells. Traffic light peptides constitute a new tool to control cell signaling in spatiotemporally defined patterns and can be used to dissect the role of clathrin-mediated endocytosis in receptor internalization and in cell growth, division, and differentiation.