We thank Dr. Sebastian Meier and Dr. Michael Pittelkow for helpful discussions. We acknowledge the Danish Instrument Center for NMR Spectroscopy of Biological Macromolecules at the Carlsberg Laboratory, where the 800 MHz spectra were recorded.
Nature’s Dendrimer: Characterizing Amylopectin as a Multivalent Host†
Article first published online: 2 SEP 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 52, Issue 43, pages 11265–11268, October 18, 2013
How to Cite
Beeren, S. R. and Hindsgaul, O. (2013), Nature’s Dendrimer: Characterizing Amylopectin as a Multivalent Host. Angew. Chem. Int. Ed., 52: 11265–11268. doi: 10.1002/anie.201305132
- Issue published online: 14 OCT 2013
- Article first published online: 2 SEP 2013
- Manuscript Received: 14 JUN 2013
- hydrophobic effect;
- supramolecular chemistry
Hang on to those branches! Amylopectin, the major polysaccharide of starch, is a predominantly α(1,4)-linked glucan whose properties are defined by its size and the number, distribution, and length of its α(1,6)-linked branches. The amphiphilic probe HPTS-C16H33 binds to terminal helical branches longer than 12 glucose units (green), which allows for a detailed quantitative characterization of polysaccharide branching by 1H NMR spectroscopy.