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Keywords:

  • multi-photon excitation;
  • nanoparticles;
  • photoswitches;
  • upconversion;
  • UV-blocking polymers
Thumbnail image of graphical abstract

Sun block for nanoparticles: Unintentional photorelease triggered by UV light is a problem in photodynamic therapy. Encapsulating upconverting nanoparticles containing photoswitches in a UV-blocking amphiphilic polymer shuts down the one-photon process and only allows two-photon-driven photochemistry. Thus, UV light is blocked while NIR light can reach the nanoparticle core and trigger photorelease.