The potent and complex antibiotic viridicatumtoxin B is a member of the tetracycline family and exhibits impressive activity against a variety of Gram-positive bacterial strains, including methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus faecalis (shown in the background). In their Communication on page 8736 ff.,, K. C. Nicolaou et al. describe the total synthesis and structural revision of viridicatumtoxin B, thus paving the way for future molecular design, chemical syntheses, and biological investigations.
In their Communication on page 8546 ff., S. H. Yu et al. report a Ni/NiO/CoSe2 catalyst that is currently the best Pt-free electrocatalyst for the hydrogen evolution reaction in acidic medium.
Nano-sized graphene oxide flakes on graphite induce room-temperature ice growth on the substrate. In their Communication on page 8708 ff., K. P. Loh et al. show that crystal nucleation and growth can be studied in real time.
X. W. Lou, Y. Xie, et al. describe in their Communication on page 8579 ff. the fabrication of complex hollow tube-in-tube nanostructures, which are promising materials for electrocatalysts and electrodes.