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Keywords:

  • combinatorial chemistry;
  • host-guest systems;
  • molecular recognition;
  • noncovalent interactions;
  • supramolecular chemistry
Thumbnail image of graphical abstract

Making receptors to order: A small dynamic combinatorial library (DCL), formed from two dithiols in water, provides a continuous range of six receptors of different sizes. The majority of the 30 tested amines and ammonium ions amplified receptors from this library, thus spanning the complete receptor-size range and showing that this DCL provides a generic platform for the development of receptors for this important class of compounds.