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Keywords:

  • bone repair;
  • diffusiophoresis;
  • micropumps;
  • nanotechnology;
  • quantum dots
Thumbnail image of graphical abstract

Bone cracks can be detected by utilizing the damaged matrix itself as both the trigger and the fuel. A crack in a material with a high mineral content such as bone generates ion gradients, which can be utilized for active targeting and treatment. This approach to targeting a biological structure augments current methods, which are focused on biomacromolecular interactions involving proteins and nucleic acids.