Bone cracks can be detected by utilizing the damaged matrix itself as both the trigger and the fuel. A crack in a material with a high mineral content such as bone generates ion gradients, which can be utilized for active targeting and treatment. This approach to targeting a biological structure augments current methods, which are focused on biomacromolecular interactions involving proteins and nucleic acids.
If you can't find a tool you're looking for, please click the link at the top of the page to "Go to old article view". Alternatively, view our Knowledge Base articles for additional help. Your feedback is important to us, so please let us know if you have comments or ideas for improvement.