Metal/N-Heterocyclic Carbene Complexes: Opportunities for the Development of Anticancer Metallodrugs

Authors

  • Dr. Federico Cisnetti,

    1. Institut de Chimie de Clermont-Ferrand, UMR CNRS 6296, Université Blaise Pascal, BP 10448, 63000 Clermont-Ferrand (France)
    Search for more papers by this author
  • Dr. Arnaud Gautier

    Corresponding author
    1. Institut de Chimie de Clermont-Ferrand, UMR CNRS 6296, Université Blaise Pascal, BP 10448, 63000 Clermont-Ferrand (France)
    • Institut de Chimie de Clermont-Ferrand, UMR CNRS 6296, Université Blaise Pascal, BP 10448, 63000 Clermont-Ferrand (France)

    Search for more papers by this author

Errata

This article is corrected by:

  1. Errata: Corrigendum: Metal/N-Heterocyclic Carbene Complexes: Opportunities for the Development of Anticancer Metallodrugs Volume 53, Issue 9, 2269, Article first published online: 20 February 2014

Abstract

original image

Death trap: The rational design of metal/N-heterocyclic carbene complexes allows mitochondria to be targeted. Activation of several apoptotic processes (which do not include direct DNA damage) induces cell death and significant tumor suppression.

Ancillary