SEARCH

SEARCH BY CITATION

Keywords:

  • asymmetric catalysis;
  • cycloaddition;
  • inhibitors;
  • iridoids;
  • signaling pathways
Thumbnail image of graphical abstract

Cousins you can count on: An iridoid-inspired compound collection was synthesized efficiently by the resolution of cyclic enones in an asymmetric cycloaddition with azomethine ylides. The collection contained novel potent inhibitors of the Wnt and Hedgehog signaling pathways.