These authors contributed equally to this work.
Overcoming the Unexpected Functional Inversion of a PqsR Antagonist in Pseudomonas aeruginosa: An In Vivo Potent Antivirulence Agent Targeting pqs Quorum Sensing†
Version of Record online: 11 DEC 2013
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 53, Issue 4, pages 1109–1112, January 20, 2014
How to Cite
Lu, C., Maurer, C. K., Kirsch, B., Steinbach, A. and Hartmann, R. W. (2014), Overcoming the Unexpected Functional Inversion of a PqsR Antagonist in Pseudomonas aeruginosa: An In Vivo Potent Antivirulence Agent Targeting pqs Quorum Sensing. Angew. Chem. Int. Ed., 53: 1109–1112. doi: 10.1002/anie.201307547
We thank Drs. Daniele Bano and Kostoula Troullinaki (German Center for Neurodegenerative Diseases, Bonn, Germany) for providing C. elegans, Dr. Matthew Wand (Health Protection Agency, Salisbury, UK) for valuable advice regarding the G. mellonella infection model, and Dr. Andrea Braunshausen for helpful discussions. pqs=Pseudomonas quinolone signal.
- Issue online: 21 JAN 2014
- Version of Record online: 11 DEC 2013
- Manuscript Revised: 10 OCT 2013
- Manuscript Received: 27 AUG 2013
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