Cover Picture: LEGO-NMR Spectroscopy: A Method to Visualize Individual Subunits in Large Heteromeric Complexes (Angew. Chem. Int. Ed. 43/2013)
Article first published online: 2 OCT 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 52, Issue 43, page 11175, October 18, 2013
How to Cite
Mund, M., Overbeck, J. H., Ullmann, J. and Sprangers, R. (2013), Cover Picture: LEGO-NMR Spectroscopy: A Method to Visualize Individual Subunits in Large Heteromeric Complexes (Angew. Chem. Int. Ed. 43/2013). Angew. Chem. Int. Ed., 52: 11175. doi: 10.1002/anie.201308150
- Issue published online: 14 OCT 2013
- Article first published online: 2 OCT 2013
- isotopic labeling;
- LSm complex;
- methyl TROSY;
- NMR spectroscopy;
- protein structures
Large asymmetric assemblies are difficult to prepare recombinantly and result in complicated NMR spectra that cannot be analyzed in detail. Both issues are addressed simultaneously in the LEGO-NMR method described by R. Sprangers and co-workers in their Communication on page 11401 ff. The method is based on sequential co-expression of NMR active and NMR invisible protein subunits of a large assembly and significantly simplifies both amide backbone and methyl side-chain spectra.
In their Communication on page 11252 ff., K. Domen et al. present a simple method for the preparation of core–shell photocatalysts with spatially separated co-catalysts for efficient water splitting.
Crystalline semiconductor nanoribbons are obtained by unwrapping core–shell nanowires, as described by F. Patolsky et al. in their Communication on page 11298 ff. An example for such an accessible material is technologically important germanium nanoribbon structures.
In their Communication on page 11395 ff., N. Nilius et al. report that chemically inert Mo-doped CaO films activate adsorbed O2 by charge transfer. The resulting oxygen surface species then dissociate as atomic oxygen.