Cover Picture: On the Way Towards Greener Transition-Metal-Catalyzed Processes as Quantified by E Factors (Angew. Chem. Int. Ed. 42/2013)

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Abstract

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As E Factors drop it's a win-win for chemistry and the environment. In their Minireview on page 10952 ff., B. H. Lipshutz and co-workers document, by direct comparisons with transition-metal-catalyzed cross-coupling reactions from pharma, just how low they can go using a commercially available designer surfactant in water as the reaction medium. As the organic solvent usage drops, E Factors can plummet by as much as an order of magnitude. Let's get organic solvents out of organic reactions, and increase sustainability.

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As E Factors drop it's a win-win for chemistry and the environment. In their Minireview on page 10952 ff., B. H. Lipshutz and co-workers document, by direct comparisons with transition-metal-catalyzed cross-coupling reactions from pharma, just how low they can go using a commercially available designer surfactant in water as the reaction medium. As the organic solvent usage drops, E Factors can plummet by as much as an order of magnitude. Let's get organic solvents out of organic reactions, and increase sustainability.

Mesoporous Materials

The preparation of fluffy core-shell, yolk-shell, and hollow anatase nanostructures by a fluorine-free synthetic method is described by D. H. Chen, R. A. Caruso, and L. Cao in their Communication on page 10986 ff.

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Electrochemistry

In their Communication on page 11016 ff., W. Luo, Z. Zou et al. report a Ta3N5 photoanode with a high solar photocurrent that was prepared by a thermal oxidation and nitridation method.

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Natural Products

S. F. Brady and H.-S. Kang describe in their Communication on page 11063 ff. an anthracycline that is encoded by DNA from soil of the Sonora Desert. The compound is active against multidrug-resistant cancer cells and may offer a new approach to cancer therapy.

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Ancillary