We are grateful to the National Institutes of Health NIGMS (R01GM984945) and the University of Illinois at Chicago for their generous support.
Dirhodium(II) Carboxylate Catalyzed Formation of 1,2,3-Trisubstituted Indoles from Styryl Azides†
Article first published online: 26 NOV 2013
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 53, Issue 3, pages 785–788, January 13, 2014
How to Cite
Jones, C., Nguyen, Q. and Driver, T. G. (2014), Dirhodium(II) Carboxylate Catalyzed Formation of 1,2,3-Trisubstituted Indoles from Styryl Azides. Angew. Chem. Int. Ed., 53: 785–788. doi: 10.1002/anie.201308611
- Issue published online: 8 JAN 2014
- Article first published online: 26 NOV 2013
- Manuscript Received: 2 OCT 2013
- National Institutes of Health. Grant Number: R01GM984945
- University of Illinois at Chicago
- electrocyclic reactions;
- synthetic methods
Dirhodium(II)-carboxylate complexes were discovered to promote the selective migration of acyl groups in trisubstituted styryl azides to form 1,2,3-trisubstituted indoles. The styryl azides are readily available in three steps from cyclobutanone and 2-iodoaniline.