pH-Responsive Micro- and Nanocarrier Systems


  • We thank the SFB 1112 of the German Research Foundation and the Helmholtz Virtual Institute for funding.


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Release on demand: The pH gradients between extra- and intracellular regions can be utilized for the controlled release of drugs and biological cargos from delivery systems. Biocompatible carrier systems with pH-cleavable units must fulfill many other criteria as well, for example, a long blood circulation time. This can be achieved by tailored micro- and nanocarriers based on macromolecular architectures or stable self-assembled systems.