We thank the National Institutes of Health for financial support (RO1 CA79954).
Tunable Visible and Near-IR Photoactivation of Light-Responsive Compounds by Using Fluorophores as Light-Capturing Antennas†
Article first published online: 27 NOV 2013
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 53, Issue 3, pages 875–878, January 13, 2014
How to Cite
Shell, T. A., Shell, J. R., Rodgers, Z. L. and Lawrence, D. S. (2014), Tunable Visible and Near-IR Photoactivation of Light-Responsive Compounds by Using Fluorophores as Light-Capturing Antennas. Angew. Chem. Int. Ed., 53: 875–878. doi: 10.1002/anie.201308816
- Issue published online: 8 JAN 2014
- Article first published online: 27 NOV 2013
- Manuscript Received: 9 OCT 2013
- National Institutes of Health. Grant Number: RO1 CA79954
- drug delivery;
- energy transfer;
Although the corrin ring of vitamin B12 is unable to efficiently absorb light beyond 550 nm, it is shown that commercially available fluorophores can be used as antennas to capture long-wavelength light to promote scission of the CoC bond at wavelengths up to 800 nm. The ability to control the molecular properties of bioactive species with long visible and near-IR light has implications for drug delivery, nanotechnology, and the spatiotemporal control of cellular behavior.