Inside Back Cover: Photosensitization of Singlet Oxygen and In Vivo Photodynamic Therapeutic Effects Mediated by PEGylated W18O49 Nanowires (Angew. Chem. Int. Ed. 47/2013)

Authors

  • Poliraju Kalluru,

    1. Department of Chemistry, Frontier Research Centre on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan (Republic of China)
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  • Dr. Raviraj Vankayala,

    1. Department of Chemistry, Frontier Research Centre on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan (Republic of China)
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  • Prof. Chi-Shiun Chiang,

    1. Department of Biomedical Engineering and Environmental, Sciences, National Tsing Hua University, Hsinchu, Taiwan (Republic of China)
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  • Prof. Kuo Chu Hwang

    Corresponding author
    1. Department of Chemistry, Frontier Research Centre on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan (Republic of China)
    • Department of Chemistry, Frontier Research Centre on Fundamental and Applied Sciences of Matters, National Tsing Hua University, Hsinchu, Taiwan (Republic of China)

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Abstract

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W18O49 nanowires can sensitize the formation of singlet oxygen upon irradiation with near-infrared (NIR) light. In their Communication on page 12332 ff., K. C. Hwang and co-workers describe the complete destruction of solid tumors in mice by W18O49-nanowire-mediated photodynamic therapy (PDT). This effect was not achieved when employing photothermal therapy or the anticancer drug doxorubicin.

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