Cover Picture: Modular Synthesis of Triarylmethanes through Palladium-Catalyzed Sequential Arylation of Methyl Phenyl Sulfone (Angew. Chem. Int. Ed. 3/2014)

Authors

  • Dr. Masakazu Nambo,

    Corresponding author
    1. Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Nagoya 464-8602 (Japan)
    • Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Nagoya 464-8602 (Japan)

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  • Dr. Cathleen M. Crudden

    Corresponding author
    1. Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Nagoya 464-8602 (Japan)
    2. Department of Chemistry, Queen's University, 90 Bader Lane, Kingston, Ontario, K7L 3N6 (Canada)
    • Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Nagoya 464-8602 (Japan)

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Abstract

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Triarylmethanes were prepared in three steps from phenyl methyl sulfone, as described by M. Nambo and C. M. Crudden in their Communication on page 742 ff. After two selective C[BOND]H arylation reactions, the third aromatic ring was introduced through a novel arylative desulfonation. This sequence permits the synthesis of a wide variety of unsymmetric triarylmethanes from a simple, readily available starting material.

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