SEARCH

SEARCH BY CITATION

Keywords:

  • amphiphiles;
  • DNA;
  • polymers;
  • self-assembly;
  • solid-phase synthesis
Thumbnail image of graphical abstract

Sequence-controlled polymers attached to DNA can be prepared by solid-phase phosphoramidite coupling, as H. F. Sleiman, C. J. Serpell, and co-workers report in their Communication on page 4567 ff. Polymers with the same molecular composition but different monomer patterns exhibit different amphiphilic self-assembly. As the DNA component still retains base-pairing fidelity, these novel conjugates encode information in two distinct, and orthogonal, assembly languages.