Inside Cover: Tuning the Composition of AuPt Bimetallic Nanoparticles for Antibacterial Application (Angew. Chem. Int. Ed. 31/2014)

Authors

  • Dr. Yuyun Zhao,

    1. Beijing Engineering Research Center for BioNanotechnology, CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, 11 Beiyitiao, ZhongGuanCun, Beijing 100190 (China)
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    • These authors contributed equally to this work.

  • Chunjie Ye,

    1. Beijing Engineering Research Center for BioNanotechnology, CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, 11 Beiyitiao, ZhongGuanCun, Beijing 100190 (China)
    2. Wuhan Institute of Technology, Xiongchu Avenue, Wuhan, 430073 (China)
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    • These authors contributed equally to this work.

  • Dr. Wenwen Liu,

    1. Beijing Engineering Research Center for BioNanotechnology, CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, 11 Beiyitiao, ZhongGuanCun, Beijing 100190 (China)
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  • Prof. Rong Chen,

    1. Wuhan Institute of Technology, Xiongchu Avenue, Wuhan, 430073 (China)
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  • Prof. Xingyu Jiang

    Corresponding author
    1. Beijing Engineering Research Center for BioNanotechnology, CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, 11 Beiyitiao, ZhongGuanCun, Beijing 100190 (China)
    • Beijing Engineering Research Center for BioNanotechnology, CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, 11 Beiyitiao, ZhongGuanCun, Beijing 100190 (China)===

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Abstract

original image

Some metals such as Ag and Hg are well known to have intrinsic antibacterial properties, but these metals are also toxic. X. Jiang and co-workers report a new class of nontoxic AuPt bimetallic nanoparticles with potent antibacterial properties in their Communication on page 8127 ff. The antibiotic mechanism includes the rupture of the inner bacterial membrane and an increase in intracellular adenosine triphosphate (ATP) levels, but does not involve the generation of reactive oxygen species.

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