Boat Conformation of cyclo-[L-Pro2-D-Pro] (pages 538–539)
Dr. Jan Willem Bats, Dipl.-Chem. Axel Friedrich, Prof. Dr. Hartmut Fuess, Prof. Dr. Horst Kessler, Dipl.-Chem. Werner Mästle and Prof. Dr. Manfred Rothe
Version of Record online: 22 DEC 2003 | DOI: 10.1002/anie.197905381
Conformational studies on small cyclic peptides are particulary informative because such compounds have model character owing to their limited flexibility. In cyclotripeptides made up of three chiral amino acids, the same chirality leads to the crown from, whereas differing chirality should lead to the boat from. This was confirmed for cyclo-[L-Pro2-D-Pro] in solution and in the solid state.