Angewandte Chemie International Edition in English

Cover image for Vol. 34 Issue 15

August 18, 1995

Volume 34, Issue 15

Pages 1533–1653

Currently known as: Angewandte Chemie International Edition

    1. Cover Picture (Angew. Chem. Int. Ed. Engl. 15/1995)

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515311

      Thumbnail image of graphical abstract

      The cover picture shows a tobacco plant (Nicotiana tabacum), the chemical formula of jasmonic acid, and two gas chromatograms. The upper chromatogram shows the pattern of volatiles emitted by an untreated plant; the lower chromatogram was obtained from a plant previously treated with the phytohormone jasmonic acid. Clearly, after incubation numerous volatile substances are biosynthesized and released into the air. These induced volatiles, which include mono- and sesquiterpenes, acetogenins, aromatic alcohols and esters, and indole, serve in plant defense and may function as interplant warning signals in particular cases. W. Boland et al. describe the effect of jasmonic acid on tobacco and other selected plants on pp. 1600–1602. Professor Wilhelm Barthlott, Bonn (Germany), provided the picture of the tobacco plant.

  1. Reviews

    1. Top of page
    2. Reviews
    3. Highlights
    4. Communications
    5. Corrigenda
    6. Book Reviews
    1. Structure and Bonding in Organometallic Anions of Heavy Group 14 and 15 Elements (pages 1545–1554)

      Michael A. Paver, Christopher A. Russell and Dr. Dominic S. Wright

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515451

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      Only four unique designators, or combinations of them, are needed to describe and classify the hydrogen-bond patterns in organic crystals: rings (as in the rhombohedral form of acetamide shown here), chains, discrete motifs, and intramolecular motifs. The procedures for developing these descriptions are presented, as well as their use in recognizing and defining hydrogen-bond pattern functionalities that cross the traditional boundaries of chemical functionality, with the purpose of describing molecular recognition and other nonbonding interactions.

    2. Patterns in Hydrogen Bonding: Functionality and Graph Set Analysis in Crystals (pages 1555–1573)

      Prof. Dr. Joel Bernstein, Prof. Dr. Raymond E. Davis, Liat Shimoni and Dr. Ning-Leh Chang

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515551

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      New reactions, new structures, and new bonding situations characterize the chemistry described in this review. Until a few years ago the existence of compounds with bonds between “early” main group metals and p block metals had not been confirmed unequivocally; now Ph3SnLi, for example, has been structurally characterized by X-ray diffraction. The [Cp5Pb2] ion (shown on the right) present in the complex [Li([12]crown-4)2]2[Cp5Pb2][Cp9Pb4] is typical for this new branch of “organometallic coordination chemistry”.

  2. Highlights

    1. Top of page
    2. Reviews
    3. Highlights
    4. Communications
    5. Corrigenda
    6. Book Reviews
    1. Exciting Results from the Field of Homogeneous Two-Phase Catalysis (pages 1575–1577)

      Prof. Dr. Boy Cornils

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515751

      The advantages of aqueous two-phase catalysis–-easy separation of the catalyst, resource-saving procedures, etc.—can, according to very recent research, even be used when the solubility of the starting materials in water is low and the transfer of the organic substrate into the aqueous phase or at least to the phase boundary is hindered. The application of “promotor ligands” or of catalysts with partly perfluorinated ligands enables homogeneous two-phase catalysis, which ideally combines the advantages of homogeneous and heterogeneous catalysis.

    2. New Dimensions in the Sol–Gel Process (pages 1578–1579)

      Prof. Dr. Hans Reuter and Maria-Theresia Brandherm

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515781

      Thumbnail image of graphical abstract

      Particularly thin oxide layers of 4.3 nm—previously the layer thickness was at least 50 nm—were obtained with a new procedure of the solution sol–gel process (SSG). Here, the metal alkoxide is spread as a film on an aqueous phase and can thus be hydrolyzed on both sides of the film (shown on the right). These thin films can also be readily transferred onto other substrates. Furthermore, the SSG process has enabled the preparation of tubes with outer diameters of 0.05–1.00 μm for the first time.

  3. Communications

    1. Top of page
    2. Reviews
    3. Highlights
    4. Communications
    5. Corrigenda
    6. Book Reviews
    1. Transition Metal Catalyzed Dimerization of Allenyl Ketones (pages 1581–1583)

      Dr. A. Stephen K. Hashmi

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515811

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      Astounding regioselectivity and good yields of the 2,4-disubstituted furans 2 are obtained by the Pd-catalyzed cycloisomerization/dimerization of readily accessible terminal allenyl ketones 1 (R = alkyl, aryl). Compounds 2 are formed exclusively with an (E)-configurated trisubstituted double bond at C4. Remarkably, the allenyl ketones 1 with R = α-haloalkyl and iodoaryl react smoothly to give 2.

    2. A Cycloaddition–Cyclodehydrogenation Route from Stilbenoids to Extended Aromatic Hydrocarbons (pages 1583–1586)

      Dipl.-Chem. Markus Müller, Dipl.-Chem. Heike Mauermann-Düll, Dr. Manfred Wagner, Dr. Volker Enkelmann and Prof. Dr. Klaus Müllen

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515831

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      An unconventional route to planar graphitic fragments has been demonstrated with the novel synthesis of aromatic polycycles such as 2. The intramolecular Diels–Alder reaction of 1 is followed by aromatization and oxidative aryl–aryl coupling to afford 2 (C30H16) in high yield. The analogous synthesis of a C54H22 polyarene shows that this approach can be used to prepare larger graphitic sections.

    3. XeOFmath image, an Anion with Pentagonal-Pyramidal Structure (pages 1586–1587)

      Dr. Arkady Ellern and Prof. Dr. Konard Seppelt

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515861

      Thumbnail image of graphical abstract

      Only minimally distorted by interionic forces in the crystal, the ion XeOFmath image (picture on the right, bond lengths in pm) can be crystallized as NO+XeOFmath image. The xenon atom is situated only slightly above the plane through the fluorine atoms, and the doubly bonded oxygen atom occupies the apical position of the pentagonal pyramid. NO+XeOFmath image is formed directly by treatment of NOF with an equimolar amount of XeOF4 and crystallizes spontaneously from the liquid phase.

    4. Hydroxylation of Alkanes with Molecular Oxygen Catalyzed by a New Ruthenium-Substituted Polyoxometalate, [WZnRumath image(OH)(H2O)(ZnW9O34)2]11− (pages 1587–1589)

      Dr. Ronny Neumann, Dr. Alexander M. Khenkin and Mazal Dahan

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515871

      Thumbnail image of graphical abstract

      Highly selective aerobic hydroxylation of tertiary carbon centers in alkanes is catalyzed by the title polyoxometalate under mild reaction conditions [Eq. (a)]. This is of great significance, in particular in the search for ways to activate molecular oxygen in the oxidation of hydrocarbons.

    5. The Crafts–Friedel Reaction: Aromatic Alkylation within the Complex Formed upon Addition of a Gaseous Arenium Ion to an Olefin (pages 1589–1591)

      Dr. Massimiliano Aschi, Prof. Dr. Marina Attinà and Prof. Dr. Fulvio Cacace

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515891

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      The roles of electrophile and nucleophile are exchanged with respect to those in conventional Friedel–Crafts reactions (arene plus carbenium ion) in these alkylations in the gas phase; an alternative mechanism has thereby been demonstrated–-an arenium ion reacts with an olefin within the initially formed arenium–olefin complex (see scheme below).

    6. Electrochemical Evidence for Through-Space Orbital Interactions in Spiromethanofullerenes (pages 1591–1594)

      Dr. Matthias Eiermann, Robert C. Haddon, Brian Knight, Q. Chan Li, Michele Maggini, Nazario Martín, Toshinobu Ohno, Maurizio Prato, Toshiyasu Suzuki and Prof. Dr. Fred Wudl

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515911

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      The electron-accepting properties of the unsaturated spiromethanofullerene 1 are enhanced relative to those of the saturated analogue with a cyclohexanone unit and of C60. This can be attributed to through-space interactions between the addend and the carbon cluster.

    7. α-Ethoxyvinyllithium: An Unexpected Polymeric Structure—Tetrameric Subunits Linked by Li[BOND]C π Interactions (pages 1594–1596)

      Dipl.-Chem. Klas Sorger, Dr. Walter Bauer, Prof. Dr. Paul von Ragué Schleyer and Priv.-Doz. Dr. Dietmar Stalke

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515941

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      Two different Li environments characterize the solvent-free, polymeric structure of 1 in the crystal. A tetrameric chain is formed by Li atoms, which are coordinated by two O and three or five C atoms. In contrast, 1 exists as isolated tetramers in THF. The C(Li)O carbenoid character of 1 results in an elongated C[BOND]O bond and in lithium bridging.

    8. A New Family of Chiral Binaphthyl-Derived Cyclophane Receptors: Complexation of Pyranosides (pages 1596–1600)

      Dr. Sally Anderson, Dipl.-Chem. Ulf Neidlein, Dr. Volker Gramlich and Prof. François Diederich

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199515961

      Thumbnail image of graphical abstract

      Even in the presence of a protic solvent (up to 20% v/v CD3OD) the optically active cyclophane tetraanion in (R,R,R,R)-1 binds to carbohydrates such as 1-O-octyl-β-D-glycopyranoside. In addition, neutral cyclophanes with similarly highly organized cavities are suitable binders in chloroform. The macrocycles are synthesized by Glaser–Hay coupling of novel chiral diethynylated 1,1'-binaphthyl monomers.

    9. Jasmonic Acid and Coronatin Induce Odor Production in Plants (pages 1600–1602)

      Prof. Dr. Wilhelm Boland, Dipl.-Chem. Jörn Hopke, Dr. Jens Donath, Dr. Jörg Nüske and Dr. Friedemann Bublitz

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516001

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      Negative effects like defoliation and senescence (aging) are not the only phenomena triggered in plants by the phytohormone jasmonic acid (1); it also stimulates tuber growth, tendril coiling, and the release of odorous substances that can function as stress signals in plant defense. In the latter case only minute concentrations of jasmonic acid are required, for example, 100 nmol mL−1 for the tobacco plant. Even lower levels of the structurally related phytotoxin coronatin (ca. 1 nmol mL−1) induce the production and release of volatiles.

    10. Pericyclic Reactions in Nature: Spontaneous Cope Rearrangement Inactivates Algae Pheromones (pages 1602–1604)

      Prof. Dr. Wilhelm Boland, Dipl.-Chem. Georg Pohnert and Dr. Ingo Maier

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516021

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      A pheromone roughly 100 times more effective than cyclohepta-1,4-diene 2 (R = C2H5, ectocarpene) is its biosynthetic precursor 1. This thermally labile cis-disubstituted cyclopropane is the actual signaling agent of the marine brown algae Ectocarpus siliculosus. The [3,3]sigmatropic rearrangement of 1 giving 2 (t1/2 = 21 min at 18°C) is the fastest known reaction for the spontaneous inactivation of a pheromone.

    11. Photoswitchable Electrical Communication of Glucose Oxidase and Glutathione Reductase with Electrode Surfaces through Photoisomerizable Redox Mediators (pages 1604–1606)

      Mazzi Lion-Dagan, Sharon Marx-Tibbon, Dr. Eugenii Katz and Prof. Itamar Willner

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516041

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      Multiple layers of glucose oxidase (or glutathione reductase) on Au electrodes can be activated and deactivated reversibly by a ferrocene–nitrospiropyran (or a bipyridinium–nitrospiropyran) acting as a photoisomerizable electron relay. The anchoring of the first enzyme layer to the surface of the electrode is shown schematically below.

    12. Reversible Template-Directed Activation of Equatorial Double Bonds of the Fullerene Framework: Regioselective Direct Synthesis, Crystal Structure, and Aromatic Properties of Th-C66(COOEt)12 (pages 1607–1609)

      Iris Lamparth, Dr. Cäcilia Maichle–Mössmer and Prof. Dr. Andreas Hirsch

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516071

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      Activation by a template is the key to the very simple, high-yield synthesis of the stable, Th-symmetric C60 hexaadduct 1 (R = COOEt) from fullerene. The data from a crystal structure analysis of 1 shows an enhanced aromaticity in the remaining benzoid π-electron system relative to C60.

    13. Diodelike Current–Voltage Curves for a Single Molecule–Tunneling Spectroscopy with Submolecular Resolution of an Alkylated, peri-Condensed Hexabenzocoronene (pages 1609–1611)

      Dr. Andreas Stabel, Dipl.-Chem. Peter Herwig, Prof. Dr. Klaus Müllen and Prof. Dr. Jürgen P. Rabe

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516091

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      The electronic properties of molecules can in some cases be elucidated by scanning tunneling microscopy and spectroscopy. The current–voltage characteristics through the aromatic core of a benzocoronene molecule (1), localized with submolecular resolution, are the same those of a diode, and are caused by the properties of a single molecule in contact with two electrodes. R = n-C12H25.

    14. Reactions of Neopentyl 2,2,2-Trifluoroethanesulfonate (Tresylate) with Nucleophiles: A Model Study for the Coupling of Nucleophiles with Tresyl Agarose (pages 1612–1613)

      Prof. James F. King and Manjinder Singh Gill

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516121

      Thumbnail image of graphical abstract

      Not the carbon, nor the sulfur, but rather the hydrogen atom is the site of the attack of a mixture of a basic nucleophile and aqueous NaOH on neopentyl tresylate (1). The elimination–addition sequence is shown below. These observations strongly suggest that the structures assigned to affinity chromatography substrates derived from tresyl agarose should be revised.

    15. Diphosphanyl- and Diarsanyl-Substituted Carbene Homologues: Germanediyls, Stannanediyls, and Plumbanediyls with Remarkable Electronic Structures (pages 1614–1616)

      Priv.-Doz. Dr. Matthias Driess, Prof. Dr. Rudolf Janoschek, Dr. Hans Pritzkow, Stefan Rell and Dr. Uwe Winkler

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516141

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      The unusual, deep green color of the crystalline, stable singlet carbene homologues 14 reflects the significant destabilization of the HOMOs relative to those of other known homologues. Compounds 14 are monomeric both in the solid state and in solution, not least because surprisingly, no donor–acceptor interactions are formed between the F atoms of the sterically demanding groups R1 and the electron-deficient metal centers E. R1 = Si(2,4,6-iPr3C6H2)2F, Si(tBu)(2,4,6-iPr3C6H2)F; R2 = SiiPr3.

    16. Biosyntheses of Novel Emycins from the Mutant Strain Streptomyces cellulosae ssp. griseoincarnatus 1114-2 (pages 1617–1621)

      Dipl.-Chem. Martin Gerlitz, Dipl.-Ing. Györgyi Udarnoki and Priv.-Doz. Dr. Jürgen Rohr

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516171

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      Natural products such as 1 with unprecedented molecular frameworks are produced by the mutant 1114-2 of Streptomyces cellulosae ssp. griseoincarnatus (FH-S 1114). Biosynthetic investigations on this genetically modified strain show that the changes at the molecular level are caused mainly by the influence of an oxygenase. Moreover, an unusual rearrangement is also involved in the generation of the product palette.

    17. β-Cycloaltrin: A Cyclooligosaccharide Consisting of Seven α(1 [RIGHTWARDS ARROW] 4)-Linked Altropyranoses (pages 1621–1622)

      Prof. Kahee Fujita, Hideaki Shimada, Kazuko Ohta, Prof. Yasuyoshi Nogami, Kyoko Nasu and Prof. Toshitaka Koga

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516211

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      A surprisingly simple approach—heating per-2,3-anhydro-(2S)-β-cyclodextrin in water at reflux—provides the novel cyclooligosaccharide β-cycloaltrin (1) in 73% yield. In this one-step hydrolysis, ring opening results in the altro configuration in every sugar unit. The inclusion properties of 1 should be interesting.

    18. Novel Biological Copper Proteins through Anion Addition to the Mutant Met121Gly of Pseudomonas aeruginosa Azurin (pages 1622–1624)

      Momcilo Vidakovic and Prof. Juris P. Germanas

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516221

      Azide, cyanide, and thiocyanate are the anions that, on addition to a variant produced by site-directed mutagenesis, Met121Gly, of Pseudomonas aeruginosa azurin, produce unprecedented copper proteins with markedly different spectroscopic properties. This ability to generate ligand-accessible metal centers in coordinatively saturated metalloproteins by directed mutagenesis might possibly bring the synthesis of metalloproteins that can be used as ion sensors a step nearer.

    19. A Redox-Switchable Hemilabile Ligand: Electrochemical Control of the Coordination Environment of a RhI Complex (pages 1624–1627)

      Elizabeth T. Singewald, Prof. Chad A. Mirkin and Charlotte L. Stern

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516241

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      Electrochemical control over the ligand sphere of transition metals is achieved with a new class of redox-switchable hemilabile ligands (RHL). Electrochemical oxidation of the RHL[BOND]Rh1 complex 1 results in a dimerization to 2. In solution at low concentrations, 1 is the dominant species, while at higher concentrations and in the solid state, the reduced form of 2 (= 2 + 4e) is favored. Fc = ferrocenyl; the counterion is BFmath image.

    20. Synthesis and Reactions of Vinyl Isoselenocyanates (pages 1627–1629)

      Prof. Dr. Klaus Banert and Dipl.-Chem. Christoph Toth

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516271

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      [3,3]Sigmatropic selenocyanate [RIGHTWARDS ARROW] isoselenocyanate rearrangements lead to the first synthesis of compounds in which the sensitive functional group–NCSe is directed into a vinylic position. The allenes 1 (R1, R2 = H or Me), and the buta-1,3-dienes 2 (R = H, Me) and 3, can be used for the preparation of selenazoles as well as for cycloadditions and deselenations to form isocyanides.

    21. Photochemically Initiated Protein Splicing (pages 1629–1630)

      Sandra N. Cook, Dr. William E. Jack, Dr. Xiaofeng Xiong, Lora E. Danley, Prof. Jonathan A. Ellman, Prof. Peter G. Schultz and Dr. Christopher J. Noren

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516291

      More details on the mechanism of protein splicing were revealed from the substitution of O-(2-nitrobenzyl)serine for the conserved Ser1082 at the upstream splice junction of the self-splicing DNA polymerase of Thermococcus litoralis. Full length precursor protein was produced, which underwent protein splicing only upon photolysis.

    22. Mesogenic Properties of Amphiphilic Liquid Crystals with an Unusual Head-Group Topology (pages 1631–1633)

      Frank Hildebrandt, Jörg Andreas Schröter, Prof. Dr. Carsten Tschierske, Reinhard Festag, Dr. Ralf Kleppinger and Prof. Dr. Joachim Heinz Wendorff

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516311

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      The lateral fixing of calamitic mesogens through hydrogen bonding of facial amphiphiles is a novel way of generating smectic materials with a broad mesomorphic region. Compound 1 is an example of this amphiphile and represents a new type of liquid-crystalline carbohydrate. R = OC10H21.

    23. Bromides of Rare Earth Metal Boride Carbides—A System of Building Blocks (pages 1633–1635)

      Dr. Hansjürgen Mattausch and Prof. Dr. Arndt Simon

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516331

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      The first examples of an expectedly large class of rare earth carbide halides are the new compounds Gd4Br3C2B, La3Br2C2B, and Ce6Br3C3B2. Their structures contain low-dimensional fragments of the three-dimensional network of metal boride carbides; typical building units are discrete C atoms, and B[BOND]C, C[BOND]B[BOND]B[BOND]C, and C[BOND]B[BOND]C groups. The projection of the structure of Gd4Br3C2B along [010] is shown on the right. • = B, ○ = C, ○ = Gd.

    24. A New Application of Capillary Zone Electrophoresis: Determination of Energy Barriers of Configurationally Labile Chiral Compounds (pages 1635–1636)

      Dipl.-Chem. Gerald Weseloh, Dipl.-Chem. Christian Wolf and Prof. Dr. Wilfried A. König

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516351

      Thumbnail image of graphical abstract

      The direct determination of the rates of racemization of configurationally labile, chiral compounds like 1 is now possible with capillary zone electrophoresis. The method obviates the isolation of the enantiomers before the enantiomerization experiment, which is required in chiroptical methods, and the computer simulations necessary for dynamic procedures.

    25. Self-Assembling Discotic Mesogens (pages 1637–1638)

      Dr. Ralf Kleppinger, Prof. Dr. C. Peter Lillya and Dr. Changquing Yang

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516371

      Thumbnail image of graphical abstract

      Columnar mesophases are formed by the diskshaped dimers of 6(5H)-phenanthridinones 1 (R = n-C8H17, n-C10H21, n-C12H25). The stacks of self-organized dimers are packed in a hexagonal arrangement. On cooling from the isotropic phase the growth of the liquid crystal is dendritic, which is typical for the formation of columnar phases.

    26. Disaccharide Mimetics by Enzymatic Tandem Aldol Additions (pages 1639–1641)

      Dr. Oliver Eyrisch and Prof. Dr. Wolf-Dieter Fessner

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516391

      Thumbnail image of graphical abstract

      Tail-to-tail C,C-coupled pyranoses or furanoses like 2 with a disaccharide-like structure were obtained from hydroxylated dialdehydes like 1 under aldolase catalysis. The key step is the twofold addition of dihydroxyacetone phosphate. As many as six stereocenters in the products can be controlled by a thermodynamically selective reaction mode.

    27. closo-[B5H4PPh3{Fe(CO)3}{Ir(CO)2PPh3}]: The First Structurally Characterized closo-Heterobimetallaheptaborane System (pages 1641–1643)

      Dr. Jonathan Bould, Dr. Nigam P. Rath and Prof. Lawrence Barton

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516411

      Thumbnail image of graphical abstract

      A pentagonal-pyramidal B5Ir moiety capped by a Fe(CO)3 group describes the title compound 1. The closo-B5FeIr cluster forms from the reaction between the iridahexaborane nido-[B5H8{Ir(CO)(PPh3)2}] and [Fe2(CO)9], and was characterized by NMR spectroscopy and single-crystal X-ray diffraction.

    28. Enantiospecific Syntheses of Valiolamine and its (1R), (2R), (1R, 2R) Diastereomers from (−)-Quinic Acid (pages 1643–1645)

      Dr. Tony K. M. Shing and Leong H. Wan

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516431

      Thumbnail image of graphical abstract

      Applicable also for other pseudosugars, the simple reaction sequence for the preparation of α-D-glucosidase inhibitors valiolamine (1) and its three diastereoisomers starts with 1,3,4,5-tetrahydroxycyclohexanecarboxylic acid (quinic acid). Glycosidase inhibitors like 1 are used as chemotherapeutics, for example, against HIV.

    29. Preparation of a Surface-Active Chiral Diphosphane and Its Use in the Hydrogenation of Prochiral Olefins (pages 1645–1647)

      Hao Ding, Prof. Brian E. Hanson and Prof. József Bakos

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516451

      Thumbnail image of graphical abstract

      Sulfonation of chiral aryl phosphanes occurs readily in high yields when they contain C6H4-p-(CH2)3-C6H5 groups. The diphosphane 1 synthesized in this way is surface active and increases the activity and selectivity of Rh catalysts for the hydrogenation of cinnamic acid derivatives in two-phase systems.

    30. (CuI)3P12: A Solid Containing a New Polymer of Phosphorus Predicted by Theory (pages 1647–1649)

      Dr. Arno Pfitzner and Dipl.-Chem. Eva Freudenthaler

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516471

      Thumbnail image of graphical abstract

      A one-dimensional, infinite phosphorus screw consisting of P12 units is present in crystals of (CuI)3P12. Theoretical calculations had predicted that this previously unknown form of phosphorus would be thermodynamically stable. Flat shiny needles of (CuI)3P12 have now been prepared from CuI and elemental phosphorus, and the new phosphorus allotrope has been characterized by X-ray diffraction (picture on the right, P: black, Cu: shaded, and I: white circles).

  4. Corrigenda

    1. Top of page
    2. Reviews
    3. Highlights
    4. Communications
    5. Corrigenda
    6. Book Reviews
    1. You have free access to this content
      Corrigendum (page 1649)

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516491

  5. Book Reviews

    1. Top of page
    2. Reviews
    3. Highlights
    4. Communications
    5. Corrigenda
    6. Book Reviews
    1. Book Review: Diazo Chemistry I. By H. Zollinger (page 1653)

      Franz Effenberger

      Article first published online: 22 DEC 2003 | DOI: 10.1002/anie.199516531

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