The Design and Synthesis of a Scaffold for Combinatorial Chemistry Based on Bile Acid (pages 2222–2224)
Dr. Günther Wess, Klaus Bock, Horst Kleine, Dr. Michael Kurz, Dr. Wolfgang Guba, Dr. Horst Hemmerle, Dr. Eloisa Lopez-Calle, Dr. Karl-Heinz Baringhaus, Dr. Heiner Glombik, Dr. Alfons Enhsen and Dr. Werner Kramer
Version of Record online: 22 DEC 2003 | DOI: 10.1002/anie.199622221
A complete β-turn can be mimicked by the tetrapeptide mimetic 1, which can thus be built into peptides with unambiguous directionality. Mimetic 1 was prepared from chenodeoxycholic acid, and is very interesting as a building block for compound libraries of β-turn mimics. ℗ = polymer support.