Knotaxanes—Rotaxanes with Knots as Stoppers (pages 4542–4545)
Oleg Lukin, Takateru Kubota, Yoshio Okamoto, Frauke Schelhase, Albena Yoneva, Walter M. Müller, Ute Müller and Fritz Vögtle
Article first published online: 25 SEP 2003 | DOI: 10.1002/anie.200351981
Get knotted: Molecular knots have been used as stoppers in the assembly of “knotaxanes”, a new family of topologically chiral rotaxanes (see picture). Two knotaxanes were separated into enantiomers using HPLC with a chiral stationary phase and characterized by measuring their CD spectra. The chirality designation of these topological species is reminiscent of the Fischer projections of open-chain sugar acids.