Chloride Transport Across Vesicle and Cell Membranes by Steroid-Based Receptors (pages 4931–4933)
Atanas V. Koulov, Timothy N. Lambert, Rameshwer Shukla, Mahim Jain, J. Middleton Boon, Bradley D. Smith, Hongyu Li, David N. Sheppard, Jean-Baptiste Joos, John P. Clare and Anthony P. Davis
Version of Record online: 15 OCT 2003 | DOI: 10.1002/anie.200351957
Crossing the barriers: Membrane transport, a well-established phenomenon for neutral cation receptors such as valinomycin, has been demonstrated for the anion-binding “cholapods”. The cholapods promote chloride efflux from vesicles by an antiport mechanism and mediate anion flow through live cells grown as epithelia (see schematic representation).