Self-Assembly in a Bipolar Phosphocholine–Water System: The Formation of Nanofibers and Hydrogels (pages 245–247)
Karen Köhler, Günter Förster, Anton Hauser, Bodo Dobner, Ulrich F. Heiser, Friederike Ziethe, Walter Richter, Frank Steiniger, Markus Drechsler, Heiko Stettin and Alfred Blume
Article first published online: 19 DEC 2003 | DOI: 10.1002/anie.200351731
The bolaamphiphile PC-C32-PC with two phosphocholine headgroups and one long C32 alkyl chain (see the space-filling model, left) forms nanofibrils in aqueous solution at room temperature solely by hydrophobic interactions. The gels that result were studied by electron microscopy (image on the right), differential scanning calorimetry, and FT-IR spectroscopy. At higher temperatures the fibers “melt” and small aggregates form.