Multifunctional Lipid/Quantum Dot Hybrid Nanocontainers for Controlled Targeting of Live Cells (pages 5478–5483)
Gopakumar Gopalakrishnan, Christophe Danelon, Paulina Izewska, Michael Prummer, Pierre-Yves Bolinger, Isabelle Geissbühler, Davide Demurtas, Jacques Dubochet and Horst Vogel
Article first published online: 18 JUL 2006 | DOI: 10.1002/anie.200600545
Hydrophobic quantum dots can be incorporated into the bilayer membrane of lipid vesicles for selective delivery into either plasma membranes or the cytoplasm of living cells (see picture). The cell and lipid membranes can integrate any kind of hydrophobic nanoparticle whose size matches the membrane thickness, thus opening possibilities for their manipulation in nanobiotechnology applications.