Unusual Chromophore and Cross-Links in Ranasmurfin: A Blue Protein from the Foam Nests of a Tropical Frog (pages 7853–7856)
Muse Oke, Rosalind Tan Yan Ching, Lester G. Carter, Kenneth A. Johnson, Huanting Liu, Stephen A. McMahon, Malcolm F. White, Carlos Bloch Jr., Catherine H. Botting, Martin A. Walsh, Aishah A. Latiff, Malcolm W. Kennedy, Alan Cooper and James H. Naismith
Article first published online: 9 SEP 2008 | DOI: 10.1002/anie.200802901
A smurfin' good structure: The 1.16 Å resolution crystal structure of ranasmurfin, a blue protein extracted from the foam nests of the Malaysian tree frog Polypedates leucomystax, reveals unusual posttranslational chemical modifications. The chromophore involves an extended Zn-coordinated four-residue (Lys-Tyr-Tyr-Lys) inter-subunit cross-link of a kind not previously reported.