Controlled Nucleation of DNA Metallization (pages 219–223)
Christian T. Wirges, Jan Timper, Monika Fischler, Alla S. Sologubenko, Joachim Mayer, Ulrich Simon and Thomas Carell
Version of Record online: 28 NOV 2008 | DOI: 10.1002/anie.200803123
Silver-plated DNA: The deposit of a thin metal layer on biomolecules, such as DNA, requires the formation of small, “magic-sized” metal nuclei. Through the careful design of a reducing chemical functionality in the form of a dialdehyde, the nucleation process and thus the metallization step can be controlled (see scheme).