Angewandte Chemie International Edition

Cover image for Vol. 48 Issue 37

September 1, 2009

Volume 48, Issue 37

Pages 6741–6921

  1. Cover Picture

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview
    1. Cover Picture: Achieving Molecular Complexity by Organocatalytic One-Pot Strategies—A Fast Entry for Synthesis of Sphingoids, Amino Sugars, and Polyhydroxylated α-Amino Acids (Angew. Chem. Int. Ed. 37/2009) (page 6741)

      Hao Jiang, Petteri Elsner, Kim L. Jensen, Aurelia Falcicchio, Vanesa Marcos and Karl Anker Jørgensen

      Version of Record online: 26 AUG 2009 | DOI: 10.1002/anie.200990191

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      The gearing of an organocatalyzed chiral leaving group multiple cascade reaction strategy achieved molecular complexity in an efficient manner. As described by K. A. Jørgensen and co-workers in their Communication on page 6844 ff., the biologically inspired reaction led to 4,5-disubstituted isoxazoline-N-oxide products; the versatility of such building blocks is exemplified by the de novo syntheses of Ribo-phytosphingosine, an amino sugar, and polyfunctionalized α-amino acid derivatives.

  2. Inside Cover

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview
    1. Inside Cover: Ultrasensitive and Selective Colorimetric DNA Detection by Nicking Endonuclease Assisted Nanoparticle Amplification (page 6742)

      Wei Xu, Xuejia Xue, Tianhu Li, Huaqiang Zeng and Xiaogang Liu

      Version of Record online: 26 AUG 2009 | DOI: 10.1002/anie.200990192

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      The ultrasensitive and selective colorimetric detection of DNA sequences is reported by X. Liu and co-workers in their Communication on page 6817 ff. The novel and versatile approach is based on a combination of an endonuclease nicking reaction and nanoparticle amplification. The approach can be utilized to detect ultralong (e.g., 80-mer) oligonucleotides with single base mismatch selectivity and a 1000-fold improvement in amplification, without complex procedures involving expensive instrumentation.

  3. Graphical Abstract

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview
  4. News

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview
  5. Author Profile

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview
    1. Robert S. Langer (pages 6760–6762)

      Version of Record online: 26 AUG 2009 | DOI: 10.1002/anie.200904208

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      “In a nutshell, my research involves biomaterials and chemical and biomedical engineering. My work is significant because it hopefully helps people to live healthier lives. …” This and more about Robert S. Langer can be found on page 6762.

  6. Meeting Review

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview
  7. Book Review

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview
    1. Modern Arylation Methods. Edited by Lutz Ackermann. (page 6768)

      Marko Hapke

      Version of Record online: 26 AUG 2009 | DOI: 10.1002/anie.200903416

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      Wiley-VCH, Weinheim 2009. 543 pp., hardcover € 149.00.—ISBN 978-3527319374

  8. Highlights

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview
    1. Natural Products

      Thiopeptide Antibiotic Biosynthesis (pages 6770–6773)

      Hans-Dieter Arndt, Sebastian Schoof and Jin-Yong Lu

      Version of Record online: 17 JUN 2009 | DOI: 10.1002/anie.200901808

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      Tailors at work: The structurally intriguing thiopeptide antibiotic natural products have been conclusively and universally shown to be biosynthesized from genetically encoded linear precursor peptides by novel tailoring enzymes. These unique findings challenge previously accepted biosynthesis paradigms and are expected to inspire future discoveries in the chemistry and biology of peptide natural products.

    2. Gallium Clusters

      Main-Group-Metal Clusters Stabilized by N-Heterocyclic Carbenes (pages 6774–6776)

      Robert Wolf and Werner Uhl

      Version of Record online: 14 JUL 2009 | DOI: 10.1002/anie.200902287

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      Carbene is key: Utilization of an N-heterocyclic carbene ligand permitted access to the neutral, octahedral closo cluster 1, a prototype of a new class of carbene-stabilized main-group-element clusters. Quantum chemical methods lend insight into the bonding situation in such clusters and reveal systematic relationships.

    3. Photonic Crystals

      Towards Large-Scale Photonic Crystals with Tuneable Bandgaps (pages 6777–6778)

      Thomas Hellweg

      Version of Record online: 7 AUG 2009 | DOI: 10.1002/anie.200902742

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      The defect tolerance of soft poly(N-isopropylacrylamide) microgels makes them good candidates for the synthesis of large colloidal crystals, which show no lattice defects, even in the presence of large dopant particles (see picture, the single dopant particle is circled). This result, together with progress in core–shell microgels with inorganic cores, should allow the preparation of photonic crystals with tunable bandgaps.

  9. Minireview

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview
    1. Enzyme Mechanisms

      Radical and Electron Recycling in Catalysis (pages 6779–6787)

      Wolfgang Buckel

      Version of Record online: 21 JUL 2009 | DOI: 10.1002/anie.200900771

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      One way or another: Radicals open new reaction pathways (1[RIGHTWARDS ARROW]2 and 1[RIGHTWARDS ARROW]4) that two-electron steps cannot achieve (1[RIGHTWARDS ARROW]3). Whereas 4 is formed by transient one-electron oxidation and two deprotonations, the addition of water to 1 to form 2 requires a high-energy electron as a cofactor that is recycled after each turnover. Organic chemists have recently applied the same principle that nature invented three billion years earlier.

  10. Review

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview
    1. Analytical Chemistry

      Virus-Based Chemical and Biological Sensing (pages 6790–6810)

      Chuanbin Mao, Aihua Liu and Binrui Cao

      Version of Record online: 7 AUG 2009 | DOI: 10.1002/anie.200900231

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      Phages and other viruses can be genetically or chemically modified to bear a motif that can selectively recognize analytes such as explosives, proteins, bacteria, spores, and toxins. Such target-specific viruses can be immobilized on a sensor chip and integrated into an analytical device. The binding of the target analyte by the viruses leads to the generation of a readable signal from a transducer in the analytical device.

  11. Communications

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview
    1. Chemical Hydrogen Storage

      Efficient Regeneration of Partially Spent Ammonia Borane Fuel (pages 6812–6816)

      Benjamin L. Davis, David A. Dixon, Edward B. Garner, John C. Gordon, Myrna H. Matus, Brian Scott and Frances H. Stephens

      Version of Record online: 9 JUN 2009 | DOI: 10.1002/anie.200900680

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      Going full circle: Ammonia borane is a potential H2-releasing fuel. Polyborazylene, a form of the spent fuel, can be regenerated efficiently in a one-pot process by the stepwise addition of appropriate digesting and reducing agents. A unique feature of this process is the formation of NH3, which is retained by some of the digested species.

    2. Boron Mimetics

      Boron Mimetics: 1,2-Dihydro-1,2-azaborines Bind inside a Nonpolar Cavity of T4 Lysozyme (pages 6817–6819)

      Lijun Liu, Adam J. V. Marwitz, Brian W. Matthews and Shih-Yuan Liu

      Version of Record online: 17 AUG 2009 | DOI: 10.1002/anie.200903390

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      Enzymes BN tricked: High-resolution protein crystallography indicates that unnatural 1,2-dihydro-1,2-azaborines bind inside the nonpolar cavity of T4 lysozyme L99A (see picture) in a fashion that is very similar to the binding of their “natural” all-carbon isosteres. These studies show that 1,2-azaborines can serve as boron-containing, hydrophobic arene mimics in biomedical research.

    3. DNA Junctions

      Substrate-Assisted Assembly of Interconnected Single-Duplex DNA Nanostructures (pages 6820–6823)

      Shogo Hamada and Satoshi Murata

      Version of Record online: 17 AUG 2009 | DOI: 10.1002/anie.200902662

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      From a T-shaped DNA junction to various DNA nanostructures (see picture, scale bar=100 nm): This technique overcomes limitations in the available varieties of DNA nanostructures and provides a well-defined geometry for structural design. Moreover, these structures can grow over the whole substrate surface in a substrate-assisted assembly method.

    4. Nanostructures

      Synthesis of Out-of-Substrate Au–Ag Nanoplates with Enhanced Stability for Catalysis (pages 6824–6827)

      Yugang Sun and Changhui Lei

      Version of Record online: 17 AUG 2009 | DOI: 10.1002/anie.200902305

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      Gold plated: Gold–silver alloy nanoplates (see image) with out-of-substrate orientation are synthesized on large-area supports by growth of silver nanoplates on gallium arsenide wafers followed by an overgrowth and alloying process. The surfaces of the nanoplates are highly exposed to the surrounding environment, thus increasing their catalytic efficiency.

    5. Lysate Assays

      Monitoring Protein Kinases in Cellular Media with Highly Selective Chimeric Reporters (pages 6828–6831)

      Elvedin Luković, Elizabeth Vogel Taylor and Barbara Imperiali

      Version of Record online: 13 AUG 2009 | DOI: 10.1002/anie.200902374

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      The best of both worlds: Combining a recombinant docking domain (see picture, blue ribbon) with a chemical sensing module (green hexagons) yields a highly selective ERK sensor. This probe exclusively monitors ERK1/2 activity in unfractionated cell lysates without any off-target kinase inhibitors. Good selectivity and biophysical parameters allow high-throughput analysis of ERK1/2 activity without time-consuming enzyme purification.

    6. Microfluidics

      Dilution-Free Analysis from Picoliter Droplets by Nano-Electrospray Ionization Mass Spectrometry (pages 6832–6835)

      Ryan T. Kelly, Jason S. Page, Ioan Marginean, Keqi Tang and Richard D. Smith

      Version of Record online: 17 AUG 2009 | DOI: 10.1002/anie.200902501

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      Packaged, transferred, and delivered: A method has been developed that automatically transfers the contents of oil-encapsulated aqueous plugs to a co-flowing aqueous stream, which enables dilution-free electrospray ionization (ESI) mass spectrometric analysis for droplet-based microfluidics.

    7. Olefination

      Recycling the Waste: The Development of a Catalytic Wittig Reaction (pages 6836–6839)

      Christopher J. O'Brien, Jennifer L. Tellez, Zachary S. Nixon, Lauren J. Kang, Andra L. Carter, Stephen R. Kunkel, Katherine C. Przeworski and Gregory A. Chass

      Version of Record online: 17 AUG 2009 | DOI: 10.1002/anie.200902525

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      It's all in the ring: 3-Methyl-1-phenylphospholane-1-oxide (4–10 mol %) and an organosilane reducing agent are the key components in the first Wittig reaction catalytic in phosphine. The protocol also functions well on larger scale: a reaction on a 30 mmol scale yielded 3.39 g of product, corresponding to a yield of 67 %.

    8. Stereoselective Catalysis

      Unusual Allylpalladium Carboxylate Complexes: Identification of the Resting State of Catalytic Enantioselective Decarboxylative Allylic Alkylation Reactions of Ketones (pages 6840–6843)

      Nathaniel H. Sherden, Douglas C. Behenna, Scott C. Virgil and Brian M. Stoltz

      Version of Record online: 11 AUG 2009 | DOI: 10.1002/anie.200902575

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      Palladium pop rocks: Hold on to your CO2! Enantioselective palladium-catalyzed decarboxylative alkylation of ketone enolates proceeds via η1-σ-allyl palladium–carboxylate complexes, such as 1 (Pd yellow, O red, N blue, P purple), by slow loss of CO2. Reminiscent of pop rock candy, impure samples of 1 expel a gas (presumably CO2) in the solid state and effervesce in solution.

    9. Asymmetric Catalysis

      Achieving Molecular Complexity by Organocatalytic One-Pot Strategies—A Fast Entry for Synthesis of Sphingoids, Amino Sugars, and Polyhydroxylated α-Amino Acids (pages 6844–6848)

      Hao Jiang, Petteri Elsner, Kim L. Jensen, Aurelia Falcicchio, Vanesa Marcos and Karl Anker Jørgensen

      Version of Record online: 13 MAY 2009 | DOI: 10.1002/anie.200901446

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      Simple complexity: By developing an organocatalyzed chiral leaving group strategy, molecular complexity was rapidly and efficiently achieved from simple starting materials. The 4,5-disubstituted isoxazoline-N-oxide products, obtained in high yield and enantioselectivity from an organocatalyzed one-pot, three-step sequence, served as versatile building blocks for natural products (see scheme).

    10. DNA Detection

      Ultrasensitive and Selective Colorimetric DNA Detection by Nicking Endonuclease Assisted Nanoparticle Amplification (pages 6849–6852)

      Wei Xu, Xuejia Xue, Tianhu Li, Huaqiang Zeng and Xiaogang Liu

      Version of Record online: 28 MAY 2009 | DOI: 10.1002/anie.200901772

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      One–two punch: Single stranded DNA sequences can be detected by nicking endonuclease assisted nanoparticle amplification (see picture). The detection system offers a colorimetric detection limit of 0.5 fmol within hours for selected oligonucleotides. Detection of DNA sequences with a single base mismatch or different lengths is also demonstrated.

    11. Metal Switches

      Cobalt(II)-Responsive DNA Binding of a GCN4-bZIP Protein Containing Cysteine Residues Functionalized with Iminodiacetic Acid (pages 6853–6856)

      Yusuke Azuma, Miki Imanishi, Tomoyuki Yoshimura, Takeo Kawabata and Shiroh Futaki

      Version of Record online: 4 AUG 2009 | DOI: 10.1002/anie.200902888

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      Two pairs to win: Two pairs of iminodiacetic acid (Ida) moieties were incorporated in the leucine zipper segment of the GCN4-bZIP protein in such a way that the Ida moieties of each pair were in i and i+2 positions. Complex formation of the Ida groups with CoII led to destabilization of the helical structure and thus enabled reversible switching of the binding of the protein to the target AP-1 site (see picture).

    12. Asymmetric Synthesis

      Absolute Asymmetric Reduction Based on the Relative Orientation of Achiral Reactants (pages 6857–6860)

      Alexander Kuhn and Peer Fischer

      Version of Record online: 5 AUG 2009 | DOI: 10.1002/anie.200902841

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      Interested in chirality? Absolutely! The breaking of molecular symmetry in the absence of a chiral species is known as absolute asymmetric synthesis. In a purely geometric absolute method for the enantioselective reduction of prochiral ketones, the appropriate surface of an achiral single crystal of the ketone was exposed to NaBH4, and the relative spatial orientation of the achiral reactants determined the handedness of the product (see picture).

    13. Nanosheets

      Large-Scale Soft Colloidal Template Synthesis of 1.4 nm Thick CdSe Nanosheets (pages 6861–6864)

      Jae Sung Son, Xiao-Dong Wen, Jin Joo, Jungseok Chae, Sung-il Baek, Kunsu Park, Jeong Hyun Kim, Kwangjin An, Jung Ho Yu, Soon Gu Kwon, Sang-Hyun Choi, Zhongwu Wang, Young-Woon Kim, Young Kuk, Roald Hoffmann and Taeghwan Hyeon

      Version of Record online: 17 AUG 2009 | DOI: 10.1002/anie.200902791

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      Soft as silk: Single-layered (right) and lamellar-structured two-dimensional (2D) CdSe nanocrystals (left) as thin as 1.4 nm can be prepared by a soft colloidal template method. Assembly of the 2D nanocrystals can be controlled by variation of the interaction between organic layers in soft templates. The current synthetic process is relatively easy to scale up, and multigram quantities can be obtained in a single batch.

    14. Carbon Dioxide Capture

      Highly Selective CO2 Capture in Flexible 3D Coordination Polymer Networks (pages 6865–6869)

      Hye-Sun Choi and Myunghyun Paik Suh

      Version of Record online: 19 AUG 2009 | DOI: 10.1002/anie.200902836

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      Keeping limber: Three-dimensional coordination polymers incorporating flexible pillars (see picture, left) exhibit highly selective adsorption of CO2 over N2, H2, and CH4 (see picture, right), thermal stability up to 300 °C, as well as air and water stability, and allow efficient CO2 capture, storage, and sensing.

    15. Natural Product Synthesis

      Total Synthesis of Hirsutellone B (pages 6870–6874)

      K. C. Nicolaou, David Sarlah, T. Robert Wu and Weiqiang Zhan

      Version of Record online: 15 AUG 2009 | DOI: 10.1002/anie.200903382

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      Cascading reactions, including the conversion of a TMS-epoxy tetraene 1 into the hirsutellone tricyclic core 2, feature heavily in the first total synthesis of the antituberculosis fungal metabolite hirsutellone B. TMS=trimethylsilyl, LA=Lewis acid.

    16. Amine–Boranes

      Bis(σ-amine–borane) Complexes: An Unusual Binding Mode at a Transition-Metal Center (pages 6875–6878)

      Romaeo Dallanegra, Adrian B. Chaplin and Andrew S. Weller

      Version of Record online: 17 AUG 2009 | DOI: 10.1002/anie.200903121

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      Getting a fix: Bis(σ-amine–borane) rhodium complexes featuring a new binding mode (two amine–borane ligands) have been prepared (see picture; Rh yellow, P green, B pink, N blue). These complexes undergo dehydrocoupling to afford di- or trimeric cyclic aminoboryl products.

    17. Heterocycles

      A General and Mild Palladium-Catalyzed Domino Reaction for the Synthesis of 2H-Indazoles (pages 6879–6882)

      Nis Halland, Marc Nazaré, Omar R'kyek, Jorge Alonso, Matthias Urmann and Andreas Lindenschmidt

      Version of Record online: 13 AUG 2009 | DOI: 10.1002/anie.200902323

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      Practical and highly versatile, the reaction of readily available (2-chlorophenyl)acetylene and hydrazine substrates affords substituted 2H-indazoles in just a few hours under very mild reaction conditions (see scheme; DMF=N,N-dimethylformamide). The catalyzed domino sequence consists of a regioselective coupling followed by an intramolecular hydroamination and subsequent isomerization of the resulting exocyclic bond.

    18. Icosahedral Nanoparticles

      Controllable Polyol Synthesis of Uniform Palladium Icosahedra: Effect of Twinned Structure on Deformation of Crystalline Lattices (pages 6883–6887)

      Cuncheng Li , Ryota Sato, Masayuki Kanehara, Haibo Zeng, Yoshio Bando and Toshiharu Teranishi

      Version of Record online: 17 AUG 2009 | DOI: 10.1002/anie.200902786

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      Tailored nanoparticles: Uniform Pd icosahedra (see TEM images) were controllably synthesized in high yield by a facile polyol process. Their size can be readily tailored from 15 to 42 nm by tuning the reaction parameters. The high density of twin boundaries and sharp edges on the surfaces of the Pd icosahedra could make them promising for many applications, for example, catalysis.

    19. Nanostructures

      Polymer-Functionalized Platinum-On-Gold Bimetallic Nanorods (pages 6888–6891)

      Bishnu P. Khanal and Eugene R. Zubarev

      Version of Record online: 13 AUG 2009 | DOI: 10.1002/anie.200903524

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      Plastic-wrapped: A polycrystalline shell of platinum can be deposited on single-crystalline gold rods. The surfaces of these structures can be covalently functionalized with organic molecules to form Au/Pt/PS nanorods (see picture, PS=polystyrene) which are soluble in organic solvents. The grafted polymer chains are visualized by electron microscopy and detected by 1H NMR spectroscopy.

    20. C[BOND]H Activation

      Palladium-Catalyzed Amidation of Unactivated C(sp3)[BOND]H Bonds: from Anilines to Indolines (pages 6892–6895)

      Julia J. Neumann, Souvik Rakshit, Thomas Dröge and Frank Glorius

      Version of Record online: 11 AUG 2009 | DOI: 10.1002/anie.200903035

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      Unreactive C[BOND]H to attractive C[BOND]N: A palladium-catalyzed intramolecular direct amidation of unactivated C(sp3)[BOND]H bonds combines C[BOND]H activation and C[BOND]N bond formation into one efficient process. Under the optimized conditions, an extraordinary tolerance of functional groups was observed, and numerous indoline derivatives were formed (see scheme).

    21. Biomimetic membranes

      Biomimetic Lipoglycopolymer Membranes: Photochemical Surface Attachment of Supramolecular Architectures with Defined Orientation (pages 6896–6899)

      Stefan M. Schiller, Annette Reisinger-Friebis, Heide Götz, Craig J. Hawker, Curtis W. Frank, Renate Naumann and W. Knoll

      Version of Record online: 17 AUG 2009 | DOI: 10.1002/anie.200901544

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      Polymers on parade: Using multifunctional building blocks and a sophisticated combination of nanotechnological surface preparation techniques, lipoglycopolymers have been utilized to construct a new type of biomimetic cell membrane (see scheme; LB=Langmuir–Blodgett). For the first time, the selective photochemical immobilization of multifunctional polymeric amphiphiles on metal substrates with defined orientation of the supramolecular architecture has been demonstrated.

    22. Separation of Isomers

      Pure Samples of Individual Conformers: The Separation of Stereoisomers of Complex Molecules Using Electric Fields (pages 6900–6902)

      Frank Filsinger, Jochen Küpper, Gerard Meijer, Jonas L. Hansen, Jochen Maurer, Jens H. Nielsen, Lotte Holmegaard and Henrik Stapelfeldt

      Version of Record online: 13 AUG 2009 | DOI: 10.1002/anie.200902650

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      Keep 'em separated: Stereoisomers of complex molecules generally have very different electric dipole moments for the same mass. The different dipole-moment-to-mass ratios can be exploited in the separation of these species using electric fields. The pure samples thus created offer opportunities in isomer-specific and stereoselective investigations.

    23. Microscopy

      Super-Resolution Imaging with Small Organic Fluorophores (pages 6903–6908)

      Mike Heilemann, Sebastian van de Linde, Anindita Mukherjee and Markus Sauer

      Version of Record online: 7 AUG 2009 | DOI: 10.1002/anie.200902073

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      What's your color? A universal and facile method for reversible photoswitching of commercially available Alexa Fluor and ATTO dyes spanning the entire visible range yields an optical resolution of approximately 20 nm. The intriguing simplicity of the method facilitates applications and opens avenues for multicolor super-resolution imaging in fixed and living cells.

    24. Methane Oxidation

      Solid Catalysts for the Selective Low-Temperature Oxidation of Methane to Methanol (pages 6909–6912)

      Regina Palkovits, Markus Antonietti, Pierre Kuhn, Arne Thomas and Ferdi Schüth

      Version of Record online: 4 AUG 2009 | DOI: 10.1002/anie.200902009

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      Again and again and again: The title reaction was achieved on a solid catalyst in a covalent triazine-based framework formed by trimerization of 2,6-dicyanopyridine in a ZnCl2 melt. The material possesses bipyridine units as coordination sites for platinum. It shows high activity and can be separated easily from the reaction mixture and recycled several times without significant loss of activity.

    25. Metal-Free Catalysis

      Heteroatoms Increase the Selectivity in Oxidative Dehydrogenation Reactions on Nanocarbons (pages 6913–6917)

      Benjamin Frank, Jian Zhang, Raoul Blume, Robert Schlögl and Dang Sheng Su

      Version of Record online: 7 AUG 2009 | DOI: 10.1002/anie.200901826

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      Boron makes it selective: Carbon nanotubes (CNTs) modified by boron oxide catalyze the oxidative dehydrogenation of propane to propene with remarkable selectivity. Nanocarbon can be an attractive alternative to conventional metal oxides, as it enables a feasible investigation of the reaction mechanism and provides a sustainable technology for alkane conversion.

  12. Preview

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. Meeting Review
    8. Book Review
    9. Highlights
    10. Minireview
    11. Review
    12. Communications
    13. Preview

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