A pH-Triggered, Fast-Responding DNA Hydrogel (pages 7660–7663)
Enjun Cheng, Yongzheng Xing, Ping Chen, Yang Yang, Yawei Sun, Dejian Zhou, Lijin Xu, Qinghua Fan and Dongsheng Liu
Article first published online: 8 SEP 2009 | DOI: 10.1002/anie.200902538
Y switch? A fast, pH-responsive DNA hydrogel (see picture; right) was prepared by a three-armed DNA nanostructure (left) assembling together through the formation of intermolecular i-motif structures (middle). The hydrogel can be switched to the non-gel state in minutes by simply using environmental pH changes.