Angewandte Chemie International Edition

Cover image for Vol. 49 Issue 14

March 29, 2010

Volume 49, Issue 14

Pages 2447–2637

  1. Cover Picture

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
    1. Cover Picture: Janus Microspheres for a Highly Flexible and Impregnable Water-Repelling Interface (Angew. Chem. Int. Ed. 14/2010) (page 2447)

      Shin-Hyun Kim, Su Yeon Lee and Seung-Man Yang

      Article first published online: 16 MAR 2010 | DOI: 10.1002/anie.201000770

      Thumbnail image of graphical abstract

      Janus microspheres composed of two hemispherical surfaces with distinctly different surface complexities show strongly contrasting water affinities between the two halves. As S.-H. Kim, S.-Y. Lee, and S.-M. Yang describe in their Communication on page 2535 ff., the microspheres were prepared by a simple process that commences with Pickering emulsion droplets. Placing the Janus particles at an air–water interface resulted in the formation of a highly flexible and robust superhydrophobic membrane.

  2. Inside Cover

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
    1. Inside Cover: Lewis Base Induced Reductions in Organolanthanide Chemistry (Angew. Chem. Int. Ed. 14/2010) (page 2448)

      Daniel Bojer, Ajay Venugopal, Beate Neumann, Hans-Georg Stammler and Norbert W. Mitzel

      Article first published online: 1 MAR 2010 | DOI: 10.1002/anie.201000867

      Thumbnail image of graphical abstract

      C[BOND]H activation and reduction are both apparent in the reaction of [SmIII(AlMe4)3] with the heterocycle (CyNCH2)3 (Cy=cyclohexyl). As shown by N. W. Mitzel and co-workers in their Communication on page 2611 ff., C[BOND]H bonds of methyl groups are activated to form a carbyne complex with an {(HC)Al3Sm} unit, and spontaneous reduction to samarium(II) by methyl groups can also be observed.

  3. Graphical Abstract

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
  4. News

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
  5. Author Profile

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
    1. Carlos F. Barbas III (page 2468)

      Article first published online: 12 MAR 2010 | DOI: 10.1002/anie.201000716

      Thumbnail image of graphical abstract

      “My biggest inspiration is the life work of Paul Ehrlich. My favorite subject at school was science, of course …” This and more about Carlos F. Barbas III can be found on page 2468.

  6. News

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
  7. Obituary

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
  8. Book Reviews

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
    1. Protein Targeting with Small Molecules. Chemical Biology Techniques and Applications. Edited by Hiroyuki Osada. (page 2472)

      Herbert Waldmann

      Article first published online: 23 MAR 2010 | DOI: 10.1002/anie.201000606

      Thumbnail image of graphical abstract

      John Wiley & Sons, Hoboken 2009. 297 pp., hardcover € 82.90.—ISBN 978-0470120538

    2. Fullerene Polymers. Synthesis, Properties and Applications. Edited by Nazario Martín and Franceso Giacalone. (pages 2472–2473)

      Dirk Guldi

      Article first published online: 23 MAR 2010 | DOI: 10.1002/anie.200907061

      Thumbnail image of graphical abstract

      Wiley-VCH, Weinheim 2009. 314 pp., hardcover € 129.00.—ISBN 978-3527322824

  9. Highlights

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
    1. Nucleophilic Boron

      Nucleophilicity of a Base-Stabilized Borole Anion at the Boron Center (pages 2474–2475)

      Makoto Yamashita

      Article first published online: 5 MAR 2010 | DOI: 10.1002/anie.201000386

      Thumbnail image of graphical abstract

      A piece of the π: A nucleophilic carbene-stabilized boryl anion has been prepared by reduction (see scheme). Reactions of this boracycle indicated its nucleophilicity on a π orbital of the central boron atom. The significance of this work is presented along with a background on nucleophilic boron reagents and boracycles.

    2. Active Plasmonics

      An Unusual Marriage: Coupling Molecular Excitons to Surface Plasmon Polaritons in Metal Nanostructures (pages 2476–2477)

      Parinda Vasa and Christoph Lienau

      Article first published online: 1 MAR 2010 | DOI: 10.1002/anie.201000178

      Thumbnail image of graphical abstract

      A wavy couple: Hybrid systems that consist of metallic nanostructures and active media, such as semiconductor nanostructures or molecular aggregates, may find interesting applications as nanometer-sized waveguides for light (see picture), ultrafast optical switches, or novel types of nanolasers.

  10. Essay

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
    1. Process Optimization

      The Flow’s the Thing…Or Is It? Assessing the Merits of Homogeneous Reactions in Flask and Flow (pages 2478–2485)

      Fernando E. Valera, Michela Quaranta, Antonio Moran, John Blacker, Alan Armstrong, João T. Cabral and Donna G. Blackmond

      Article first published online: 24 FEB 2010 | DOI: 10.1002/anie.200906095

      Thumbnail image of graphical abstract

      Against the flow? What factors dictate the relative merits of microflow reactors versus batch-reaction flasks for homogeneous catalytic reactions? The optimal reaction protocol must be decided on a case-by-case basis. Flask reactors equipped with in situ detection devices provide a concise and information-rich means of obtaining the intrinsic kinetic information required to make this decision.

  11. Review

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
    1. Asymmetric Catalysis

      Phosphoramidites: Privileged Ligands in Asymmetric Catalysis (pages 2486–2528)

      Johannes F. Teichert and Ben L. Feringa

      Article first published online: 23 MAR 2010 | DOI: 10.1002/anie.200904948

      Thumbnail image of graphical abstract

      A meteoric rise: After their first application in asymmetric conjugate addition reactions in 1996, phosphoramidites have developed into one of the most effective ligands in enantioselective transition-metal catalysis. A particular advantage is their modular synthesis, which allows fine-tuning for a specific catalytic reaction.

  12. Communications

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
    1. Reaction Mechanisms

      Glucose Activation by Transient Cr2+ Dimers (pages 2530–2534)

      Evgeny A. Pidko, Volkan Degirmenci, Rutger A. van Santen and Emiel J. M. Hensen

      Article first published online: 15 MAR 2010 | DOI: 10.1002/anie.201000250

      Thumbnail image of graphical abstract

      Cat waiting in the wings: The transient formation of Cr2+ dimers through coordination to a second molecule of the catalyst promotes the isomerization of glucose to fructose and explains the unique ability of CrCl2 to catalyze the dehydration of glucose to 5-hydroxymethylfurfural (HMF) in ionic-liquid media. The active-site environment during the rate-controlling step resembles that in hexose isomerase enzymes.

    2. Interfaces

      Janus Microspheres for a Highly Flexible and Impregnable Water-Repelling Interface (pages 2535–2538)

      Shin-Hyun Kim, Su Yeon Lee and Seung-Man Yang

      Article first published online: 15 MAR 2010 | DOI: 10.1002/anie.201000108

      Thumbnail image of graphical abstract

      Janus microspheres composed of superhydrophobic and hydrophilic hemispherical surfaces were prepared using photocurable Pickering emulsion droplets. Upon placement at an air–water interface, an impregnable superhydrophobic barrier with high flexibility is formed. These microspheres have great potential in size-dependent semipermeable membranes, floating micromachines, and superhydrophobic coatings.

    3. Chiral Resolution

      Enantioselective Symmetry Breaking Directed by the Order of Process Steps (pages 2539–2541)

      Wim L. Noorduin, Hugo Meekes, Willem J. P. van Enckevort, Bernard Kaptein, Richard M. Kellogg and Elias Vlieg

      Article first published online: 5 MAR 2010 | DOI: 10.1002/anie.200907231

      Thumbnail image of graphical abstract

      Going forward in reverse: The configuration of the product of grinding-induced symmetry breaking can be controlled simply by the order in which the different reaction-mixture components are combined (see scheme: I) glass beads, II) racemic mixture (enantiomers differentiated by color), III) solvent, IV) racemization catalyst). The underlying mechanism is based on a subtle balance between enantioselective crystal growth and dissolution.

    4. Ligand Effects

      Steering the Surprisingly Modular π-Acceptor Properties of N-Heterocyclic Carbenes: Implications for Gold Catalysis (pages 2542–2546)

      Manuel Alcarazo, Timon Stork, Anakuthil Anoop, Walter Thiel and Alois Fürstner

      Article first published online: 5 MAR 2010 | DOI: 10.1002/anie.200907194

      Thumbnail image of graphical abstract

      Accept it! Although the π-acceptor properties of N-heterocyclic carbenes (NHCs) are often considered negligible, they can be enhanced to the extent that they start to dominate the catalytic behavior of gold–NHC complexes (see scheme). As it seems to be easier to tune the π acidity of NHCs than to alter their σ-donor properties, the general perception of this important class of ancillary ligands needs to be revised.

    5. Deposition Techniques

      Low-Temperature ABC-Type Atomic Layer Deposition: Synthesis of Highly Uniform Ultrafine Supported Metal Nanoparticles (pages 2547–2551)

      Junling Lu and Peter C. Stair

      Article first published online: 12 MAR 2010 | DOI: 10.1002/anie.200907168

      Thumbnail image of graphical abstract

      Sheltered growth: A novel atomic layer deposition (ALD) method to synthesize highly uniform ultrafine supported metal nanoparticles is described. The ALD process includes growing protected metal nanoparticles and new support layers simultaneously at low temperature. In the final stage, the activation of the metal nanoparticles can be achieved by removing the protective ligands through calcination or reduction at elevated temperature (see picture).

    6. Antibody Delivery

      Efficient Delivery of Bioactive Antibodies into the Cytoplasm of Living Cells by Charge-Conversional Polyion Complex Micelles (pages 2552–2555)

      Yan Lee, Takehiko Ishii, Hyun Jin Kim, Nobuhiro Nishiyama, Yoshiyuki Hayakawa, Keiji Itaka and Kazunori Kataoka

      Article first published online: 5 MAR 2010 | DOI: 10.1002/anie.200905264

      Thumbnail image of graphical abstract

      Stand and deliver! Immunoglobulin G (IgG) can be delivered into the cytoplasm of living cells by charge-conversional modification followed by treatment with a cationic block copolymer to form polyion complex (PIC) micelles (see picture). The bioactivity of the IgG selectively recovers in the cell in a pH-dependent manner, thereby controlling the growth of human hepatoma cells through IgG binding to intracellular target molecules.

    7. Potentiometric Sensing

      Potentiometric Sensing of Neutral Species Based on a Uniform-Sized Molecularly Imprinted Polymer as a Receptor (pages 2556–2559)

      Rong-Ning Liang, De-An Song, Rui-Ming Zhang and Wei Qin

      Article first published online: 2 MAR 2010 | DOI: 10.1002/anie.200906720

      Thumbnail image of graphical abstract

      Sensing changes: A uniform-sized molecularly imprinted polymer (MIP), employed as a receptor, can be incorporated into a polymeric membrane used as an ion-selective electrode for the potentiometric sensing of neutral species (see scheme). Changes in the binding sites of the MIP in the membrane phase induced by recognition of the analyte are measured by using an indicator ion that has a molecular structure similar to that of the analyte.

    8. Uranium Cluster Chemistry

      Tetranuclear Uranium Clusters by Reductive Cleavage of 3,5-Dimethylpyrazolate (pages 2560–2564)

      Jeffrey D. Rinehart, Stosh A. Kozimor and Jeffrey R. Long

      Article first published online: 2 MAR 2010 | DOI: 10.1002/anie.200906605

      Thumbnail image of graphical abstract

      Hard-core uranium chemistry: The 3,5-dimethylpyrazolate anion can be activated by uranium(III) to form 4-ketimidopent-2-ene-2-imido (kipi3−) units, which are isoelectronic to acetylacetonate. Three related tetranuclear uranium cluster compounds were isolated (see picture), of which two are mixed valent.

    9. Oxygen-Reduction Catalysts

      Nitrogen-Doped Ordered Mesoporous Graphitic Arrays with High Electrocatalytic Activity for Oxygen Reduction (pages 2565–2569)

      Ruili Liu, Dongqing Wu, Xinliang Feng and Klaus Müllen

      Article first published online: 9 MAR 2010 | DOI: 10.1002/anie.200907289

      Thumbnail image of graphical abstract

      These materials are no dopes: Nitrogen-doped ordered mesoporous graphitic arrays (NOMGAs) prepared by a metal-free procedure exhibited higher electrocatalytic activity than the commercially available Pt–C catalyst (see plot), excellent long-term stability, and resistance to crossover effects in the oxygen-reduction reaction (ORR). Graphite-like nitrogen atoms appear to be responsible for the excellent electrochemical performance in the ORR.

    10. Mesoporous Anodes

      Lithium Intercalation into Mesoporous Anatase with an Ordered 3D Pore Structure (pages 2570–2574)

      Yu Ren, Laurence J. Hardwick and Peter G. Bruce

      Article first published online: 5 MAR 2010 | DOI: 10.1002/anie.200907099

      Thumbnail image of graphical abstract

      Surprising anode material! A mesoporous anatase was synthesized that showed superior rate capability. Even after 1000 charge/discharge cycles at a rate of 12 000 mA g−1 (1.6 min per cycle), the mesostructure was retained with a stable capacity of 125 mA h g−1 (see diagram).

    11. Chalcogenide Fullerenes

      Snapshots of the Formation of Inorganic MoS2 Onion-Type Fullerenes: A “Shrinking Giant Bubble” Pathway (pages 2575–2580)

      Aswani Yella, Martin Panthöfer, Michael Kappl and Wolfgang Tremel

      Article first published online: 5 MAR 2010 | DOI: 10.1002/anie.200902481

      Thumbnail image of graphical abstract

      Growing onions: Formation of onion-type MoS2 fullerenes was monitored by taking TEM snapshots of reaction intermediates in the thermal decomposition of amorphous precursor particles, which led first to giant multiwall fullerenes (d>150 nm) in which, at higher temperature, smaller daughter fullerenes segregated (see TEM image). Subsequently, tubular nanopods, containing fullerene particles and finally twinned and nested fullerenes, were formed.

    12. Hydrogen Storage

      Production of HCOOH/NEt3 Adducts by CO2/H2 Incorporation into Neat NEt3 (pages 2581–2584)

      Debora Preti, Sergio Squarcialupi and Giuseppe Fachinetti

      Article first published online: 12 MAR 2010 | DOI: 10.1002/anie.200906054

      Thumbnail image of graphical abstract

      Adding HCOOH to NEt3 gives a biphasic system of amine and an adduct with a molar acid/amine ratio (AAR) of 1.33. In the presence of a suitable catalyst, CO2/H2 (1:1) acts as HCOOH if both amine and 1.33-adduct phases are present. For example, at 40 °C and 120 bar, neat amine, “doped” with both 1.33 adduct and catalyst, is quantitatively converted into 1.78 adduct, which is distilled as an azeotrope with AAR=2.35.

    13. Total Synthesis

      Total Synthesis of Lipoteichoic Acid of Streptococcus pneumoniae (pages 2585–2590)

      Christian Marcus Pedersen, Ignacio Figueroa-Perez, Buko Lindner, Artur J. Ulmer, Ulrich Zähringer and Richard R. Schmidt

      Article first published online: 9 MAR 2010 | DOI: 10.1002/anie.200906163

      Thumbnail image of graphical abstract

      Mixed signals: The glycophospholipid 1, consisting of two cholinylphospho-GalNAc units, two 2-acetamino-4-amino-2,4,6-trideoxygalactose rings, three glucose residues each with different linkages to other sugar units, and a ribitolphosphate residue, has been synthesized. Target 1 is recognized by the immune system, but not by the TLR-2 signaling receptor as previously postulated.

    14. Asymmetric Synthesis

      Catalytic Asymmetric Synthesis of Complex Polypropionates: Lewis Base Catalyzed Aldol Equivalents in the Synthesis of Erythronolide B (pages 2591–2594)

      Binita Chandra, Dezhi Fu and Scott G. Nelson

      Article first published online: 5 MAR 2010 | DOI: 10.1002/anie.200906245

      Thumbnail image of graphical abstract

      Powerful aldol reactions: Stereoselective Lewis base catalyzed aldol equivalents expediently provided eight of the ten stereocenters required for the synthesis of erythronolide B. Indeed, all eleven stereocenters present in the erythromycin aglycone have been derived directly or indirectly from catalytic asymmetric equivalents of aldol addition reactions (see scheme).

    15. Molecular Logic

      An Electrochemically Transduced XOR Logic Gate at the Molecular Level (pages 2595–2598)

      Yaqing Liu, Andreas Offenhäusser and Dirk Mayer

      Article first published online: 12 MAR 2010 | DOI: 10.1002/anie.200906333

      Thumbnail image of graphical abstract

      Golden logic: The integration of both cathodic and anodic electrochemical current rectifiers (ECR) on a gold electrode (see picture) results in a molecular-level XOR logic gate with a high switch ratio between electrical output signals “1” and “0”. When the electrode is modified by the redox mediator ferrocene, successive XOR logic-gate functions can be carried out without resetting the system.

    16. Enzyme Inhibitors

      Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines (pages 2599–2602)

      James M. Macdonald, Chris A. Tarling, Edward J. Taylor, Rebecca J. Dennis, David S. Myers, Spencer Knapp, Gideon J. Davies and Stephen G. Withers

      Article first published online: 5 MAR 2010 | DOI: 10.1002/anie.200906644

      Thumbnail image of graphical abstract

      A good imitation: Di- and trisaccharide analogues of the oxazoline intermediate formed during enzymatic hydrolysis of chitin were found to be potent inhibitors of chitinase A. The high affinity and enzymatic stability of a readily synthesized thioamide trisaccharide (two molecules of which are shown in the enzyme active site), and the mechanism-based mode of inhibition, make this analogue a promising candidate for broad-spectrum chitinase inhibition.

    17. Enzyme Detection

      Detection of Single Enzyme Molecules inside Nanopores on the Basis of Chemiluminescence (pages 2603–2606)

      Seong Ho Kang, Seungah Lee and Edward S. Yeung

      Article first published online: 8 MAR 2010 | DOI: 10.1002/anie.200906713

      Thumbnail image of graphical abstract

      Trapped, but not immobilized inside 50 nm membrane pores, luciferase was detected on the basis of chemiluminescence (see scheme) with an intensified-charge-coupled-device (ICCD) camera. Light emission from the nanopores was concentrated onto individual pixels of the ICCD. Single-molecule detection was possible by integration of the amplified signal over a prolonged enzyme reaction time.

    18. Cycloaddition Reactions

      Direct Synthesis of 1,4-Disubstituted-5-alumino-1,2,3-triazoles: Copper-Catalyzed Cycloaddition of Organic Azides and Mixed Aluminum Acetylides (pages 2607–2610)

      Yuhan Zhou, Thomas Lecourt and Laurent Micouin

      Article first published online: 2 MAR 2010 | DOI: 10.1002/anie.200907016

      Thumbnail image of graphical abstract

      Al together now: Aluminotriazoles are obtained in a fully chemo- and regioselective manner by a copper-catalyzed cycloaddition of organic azides with mixed-aluminum acetylides (see scheme). The carbon[BOND]aluminum bond, which is unaffected by the first transformation, is still able to react further with different electrophiles.

    19. Base-Induced Reduction

      Lewis Base Induced Reductions in Organolanthanide Chemistry (pages 2611–2614)

      Daniel Bojer, Ajay Venugopal, Beate Neumann, Hans-Georg Stammler and Norbert W. Mitzel

      Article first published online: 28 FEB 2010 | DOI: 10.1002/anie.200906952

      Thumbnail image of graphical abstract

      Spontaneous reduction of samarium(III) to samarium(II) is observed upon addition of bulky cyclic triaminals to [Sm(AlMe4)3] (see scheme). The methyl groups of the organometallic precursor act as reductant, and C[BOND]H activation is found as a side reaction. This reaction is the first base-induced reduction of a lanthanide(III) complex to lanthanide(II) in the complete absence of stabilizing cyclopentadienyl systems.

    20. Protonation of Oxaphosphiranes

      Protonation-Induced Rearrangement of an Oxaphosphirane Complex (pages 2615–2618)

      Janaina Marinas Pérez, Holger Helten, Bruno Donnadieu, Christopher A. Reed and Rainer Streubel

      Article first published online: 2 MAR 2010 | DOI: 10.1002/anie.200906825

      Thumbnail image of graphical abstract

      O-Protonation of an oxaphosphirane tungsten complex causes ring opening and the formation of a P[BOND]OH functional methylene phosphonium ligand bound side-on to the tungsten center (see scheme).

    21. Biomimetic Synthesis

      Total Synthesis of Coralloidolides A, B, C, and E (pages 2619–2621)

      Thomas J. Kimbrough, Paul A. Roethle, Peter Mayer and Dirk Trauner

      Article first published online: 9 MAR 2010 | DOI: 10.1002/anie.200906126

      Thumbnail image of graphical abstract

      Mapping the matrix: Several coralloidolides, members of a Mediterranean branch of the furanocembranoid family of diterpenes, have been synthesized. The total syntheses include biomimetic transformations that often occur with high chemoselectivity, thus obviating the need for protecting-group manipulations. The fascinating reactivity of 2,5-diene-1,4-dione moieties was explored in detail.

      Corrected by:

      Corrigendum: Corrigendum: Total Synthesis of Coralloidolides A, B, C, and E

      Article first published online: 13 APR 2015

    22. Bioinorganic Enzyme Models

      Electron-Transfer Properties of an Efficient Nonheme Iron Oxidation Catalyst with a Tetradentate Bispidine Ligand (pages 2622–2625)

      Peter Comba, Shunichi Fukuzumi, Hiroaki Kotani and Steffen Wunderlich

      Article first published online: 12 MAR 2010 | DOI: 10.1002/anie.200904427

      Thumbnail image of graphical abstract

      The oxidation catalyst [(L)FeIV[DOUBLE BOND]O] (see picture; L is a tetradentate bispidine ligand) has the highest known one-electron reduction potential for a FeIV[DOUBLE BOND]O species (0.73 V vs. SCE). Investigations into the electron-transfer kinetics show a linear correlation with the bond dissociation energy of the organic substrates.

    23. Titanium Catalysis

      [Ind2TiMe2]: A Catalyst for the Hydroaminomethylation of Alkenes and Styrenes (pages 2626–2629)

      Raphael Kubiak, Insa Prochnow and Sven Doye

      Article first published online: 2 MAR 2010 | DOI: 10.1002/anie.200906557

      Thumbnail image of graphical abstract

      Metal-catalyzed hydroaminomethylations of styrenes, which take place by C[BOND]H bond activation, can be achieved in the presence of the catalyst [Ind2TiMe2] (Ind=η5-indenyl). Corresponding reactions of 1-alkenes with N-methylanilines performed at temperatures between 80 °C and 105 °C usually take place with regioselectivities of better than 99:1 in favor of the branched product.

    24. Ultrasensitive NMR Spectroscopy

      Characterization of Picomole Amounts of Oligosaccharides from Glycoproteins by 1H NMR Spectroscopy (pages 2630–2633)

      Meike Fellenberg, Atillâ Çoksezen and Bernd Meyer

      Article first published online: 2 MAR 2010 | DOI: 10.1002/anie.200906680

      Thumbnail image of graphical abstract

      Can you see it? NMR spectroscopy is indispensible for structure analysis. It is believed that its use is limited if less than several nanomoles are available. The characterization of oligosaccharides as components of glycoproteins by NMR spectroscopy utilizing significantly less material is highly desirable. Optimization of the sample preparation, water suppression, and instrument setup has enabled only 15 picomoles of oligosaccharides to be analyzed by NMR spectroscopy.

  13. Preview

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Author Profile
    7. News
    8. Obituary
    9. Book Reviews
    10. Highlights
    11. Essay
    12. Review
    13. Communications
    14. Preview
    1. You have free access to this content
      Preview: Angew. Chem. Int. Ed. 15/2010 (page 2637)

      Article first published online: 23 MAR 2010 | DOI: 10.1002/anie.201090042

SEARCH

SEARCH BY CITATION