A General and Special Catalyst for Suzuki–Miyaura Coupling Processes (pages 5879–5883)
Wenjun Tang, Andrew G. Capacci, Xudong Wei, Wenjie Li, Andre White, Nitinchandra D. Patel, Jolaine Savoie, Joe J. Gao, Sonia Rodriguez, Bo Qu, Nizar Haddad, Bruce Z. Lu, Dhileepkumar Krishnamurthy, Nathan K. Yee and Chris H. Senanayake
Version of Record online: 15 JUL 2010 | DOI: 10.1002/anie.201002404
Biaryl monophosphorus ligands containing a 2,3-dihydrobenzo[d][1,3]oxaphosphole framework are highly effective for the palladium-catalyzed Suzuki–Miyaura cross-coupling reactions of a wide range of substrates. Ligand 1 has demonstrated excellent performance for coupling reactions of extremely hindered arylboronic acids.