The Binding of Fluorophores to Proteins Depends on the Cellular Environment (pages 2761–2763)
Dr. Yun Kyung Kim, Dr. Jun-Seok Lee, Dr. Xuezhi Bi, Dr. Hyung-Ho Ha, Shin Hui Ng, Dr. Young-hoon Ahn, Dr. Jae-Jung Lee, Dr. Bridget K. Wagner, Dr. Paul A. Clemons and Prof. Dr. Young-Tae Chang
Version of Record online: 2 MAR 2011 | DOI: 10.1002/anie.201007626
Lighten up! To investigate intracellular binders of myotube-specific probes, a thiol-reactive derivative, CDy2, was prepared. In live cells, the derivative selectively localizes in mitochondria and covalently labels its binding partners.