The Largest Synthetic Structure with Molecular Precision: Towards a Molecular Object (pages 737–740)
Dr. Baozhong Zhang, Dr. Roger Wepf, Dr. Karl Fischer, Prof. Manfred Schmidt, Dr. Sébastien Besse, Dr. Peter Lindner, Prof. Benjamin T. King, Dr. Reinhard Sigel, Prof. Peter Schurtenberger, Prof. Yeshayahu Talmon, Dr. Yi Ding, Prof. Martin Kröger, Prof. Avraham Halperin and Prof. A. Dieter Schlüter
Article first published online: 22 DEC 2010 | DOI: 10.1002/anie.201005164
Pushing the limits: A 200×106 Da structurally defined, linear macromolecule (PG5) has a molar mass, cross-section dimension, and cylindrical shape that are comparable to some naturally occurring objects, such as amyloid fibrils or certain plant viruses. The macromolecule is resistant against flattening out on a surface; the picture shows PG5 embracing the tobacco mosaic virus (TMV).