Anchored Proteinase-Targetable Optomagnetic Nanoprobes for Molecular Imaging of Invasive Cancer Cells (pages 945–948)
Joseph Park, Prof. Jaemoon Yang, Eun-Kyung Lim, Eunjung Kim, Jihye Choi, Joo Kyung Ryu, Nam Hee Kim, Prof. Jin-Suck Suh, Prof. Jong In Yook, Prof. Yong-Min Huh and Prof. Seungjoo Haam
Article first published online: 12 DEC 2011 | DOI: 10.1002/anie.201106758
Activatable nanoprobe: A dual-function nanoprobe has been developed that detects membrane type 1-matrix metalloproteinase (MT1-MMP) activity by a dual-signal increase in complementary fluorescence imaging (FI) and magnetic resonance imaging (MRI). MNCs=magnetic nanocrystals, Q=quencher, F=fluorescence dye.