Rapid Access to Dibenzohelicenes and their Functionalized Derivatives (pages 9970–9975)
Andrej Jančařík, Dr. Jiří Rybáček, Kevin Cocq, Dr. Jana Vacek Chocholoušová, Dr. Jaroslav Vacek, Dr. Radek Pohl, Dr. Lucie Bednárová, Dr. Pavel Fiedler, Dr. Ivana Císařová, Dr. Irena G. Stará and Dr. Ivo Starý
Article first published online: 9 AUG 2013 | DOI: 10.1002/anie.201301739
Spiraling up: Easy access to dibenzo-, dibenzo-, and dibenzohelicenes (see picture) as well as their functionalized derivatives includes Sonogashira and Suzuki–Miyaura couplings, desilylation, and [2+2+2] alkyne cycloisomerization. The simplicity of this non-photochemical approach combined with the potential for helicity control favors dibenzohelicenes over the parent helicenes for practical applications.