Angewandte Chemie International Edition

Cover image for Vol. 53 Issue 14

April 1, 2014

Volume 53, Issue 14

Pages 3521–3747

  1. Cover Pictures

    1. Top of page
    2. Cover Pictures
    3. Graphical Abstract
    4. News
    5. Author Profile
    6. News
    7. Obituary
    8. Book Reviews
    9. Highlight
    10. Minireview
    11. Review
    12. Communications
    1. You have free access to this content
      Cover Picture: Diphenylacetylene-Linked Peptide Strands Induce Bidirectional β-Sheet Formation (Angew. Chem. Int. Ed. 14/2014) (page 3521)

      Dr. Hannah Lingard, Jeongmin T. Han, Dr. Amber L. Thompson, Dr. Ivanhoe K. H. Leung, Dr. Richard T. W. Scott, Dr. Sam Thompson and Prof. Andrew D. Hamilton

      Version of Record online: 5 MAR 2014 | DOI: 10.1002/anie.201401099

      Thumbnail image of graphical abstract

      β-Sheets, key secondary structural elements of folded proteins, are commonly involved in therapeutically important protein–protein interactions and are a critical constituent of amyloid deposits in many neurodegenerative conditions. In their Communication on page 3650 ff., A. D. Hamilton, S. Thompson, et al. reveal a strategy for mediating these interactions through the use of a tetrasubstituted diphenylacetylene to induce the formation of β-sheet structures in two directions (illustration by Dr. Karl Harrison).

    2. You have free access to this content
      Inside Cover: Electronic Ground State of Carbon at Temperatures Approaching 0 K (Angew. Chem. Int. Ed. 14/2014) (page 3522)

      Prof. Wojciech Grochala

      Version of Record online: 18 MAR 2014 | DOI: 10.1002/anie.201401115

      Thumbnail image of graphical abstract

      Diamond and graphite are two prototypical examples of allotropy. In his Communication on page 3680 ff., W. Grochala describes the results of hybrid density functional theory calculations for both forms of carbon, which point to an energetic preference for diamond at temperatures close to absolute zero but thermodynamic preference for graphite at ambient temperature (cover artwork by Dr. Karol Fijalkowski).

    3. You have free access to this content
      Inside Back Cover: Hollow Spheres of Iron Carbide Nanoparticles Encased in Graphitic Layers as Oxygen Reduction Catalysts (Angew. Chem. Int. Ed. 14/2014) (page 3749)

      M.Sc. Yang Hu, Dr. Jens Oluf Jensen, Dr. Wei Zhang, Dr. Lars N. Cleemann, Prof. Wei Xing, Prof. Niels J. Bjerrum and Dr. Qingfeng Li

      Version of Record online: 5 MAR 2014 | DOI: 10.1002/anie.201401098

      Thumbnail image of graphical abstract

      Iron carbide nanoparticles encased in thin graphitic layers are active towards oxygen reduction. In their Communication on page 3675 ff., W. Xing, Q. F. Li, and co-workers report that hollow spheres composed of these nanoparticles without surface nitrogen or metallic functionalities show high activity and stability in both acidic and alkaline media. The catalysts are synthesized in a one-step process.

    4. You have free access to this content
      Back Cover: Gas-Phase Peptide Structures Unraveled by Far-IR Spectroscopy: Combining IR-UV Ion-Dip Experiments with Born–Oppenheimer Molecular Dynamics Simulations (Angew. Chem. Int. Ed. 14/2014) (page 3750)

      Sander Jaeqx, Prof. Dr. Jos Oomens, Dr. Alvaro Cimas, Prof. Dr. Marie-Pierre Gaigeot and Dr. Anouk M. Rijs

      Version of Record online: 12 MAR 2014 | DOI: 10.1002/anie.201401109

      Thumbnail image of graphical abstract

      Soft vibrational modes are typically delocalized over the entire molecule. A far-infrared spectrum is therefore expected to contain detailed information on the global conformational structure of peptides. In their Communication on page 3663 ff., M.-P. Gaigeot, A. M. Rijs, and co-workers show that conformation-selective far-IR spectroscopic experiments combined with Born–Oppenheimer molecular dynamics (BOMD) simulations provide an alternative approach to decipher this information.

  2. Graphical Abstract

    1. Top of page
    2. Cover Pictures
    3. Graphical Abstract
    4. News
    5. Author Profile
    6. News
    7. Obituary
    8. Book Reviews
    9. Highlight
    10. Minireview
    11. Review
    12. Communications
  3. News

    1. Top of page
    2. Cover Pictures
    3. Graphical Abstract
    4. News
    5. Author Profile
    6. News
    7. Obituary
    8. Book Reviews
    9. Highlight
    10. Minireview
    11. Review
    12. Communications
  4. Author Profile

    1. Top of page
    2. Cover Pictures
    3. Graphical Abstract
    4. News
    5. Author Profile
    6. News
    7. Obituary
    8. Book Reviews
    9. Highlight
    10. Minireview
    11. Review
    12. Communications
    1. Xiong Wen (David) Lou (page 3544)

      Version of Record online: 27 MAR 2014 | DOI: 10.1002/anie.201310521

      Thumbnail image of graphical abstract

      “In a spare hour, I like to watch TV. My favorite way to spend a holiday is to go fishing …” This and more about Xiong Wen (David) Lou can be found on page 3544.

  5. News

    1. Top of page
    2. Cover Pictures
    3. Graphical Abstract
    4. News
    5. Author Profile
    6. News
    7. Obituary
    8. Book Reviews
    9. Highlight
    10. Minireview
    11. Review
    12. Communications
  6. Obituary

    1. Top of page
    2. Cover Pictures
    3. Graphical Abstract
    4. News
    5. Author Profile
    6. News
    7. Obituary
    8. Book Reviews
    9. Highlight
    10. Minireview
    11. Review
    12. Communications
    1. Sir John Warcup Cornforth (19172013) (page 3546)

      Prof. Bernard T. Golding and Prof. Wolfgang Buckel

      Version of Record online: 5 MAR 2014 | DOI: 10.1002/anie.201401077

      Thumbnail image of graphical abstract
  7. Book Reviews

    1. Top of page
    2. Cover Pictures
    3. Graphical Abstract
    4. News
    5. Author Profile
    6. News
    7. Obituary
    8. Book Reviews
    9. Highlight
    10. Minireview
    11. Review
    12. Communications
    1. Design and Strategy in Organic Synthesis. From the Chiron Approach to Catalysis. By Stephen Hanessian, Simon Giroux and Bradley Merner. (page 3547)

      Scott A. Snyder

      Version of Record online: 19 FEB 2014 | DOI: 10.1002/anie.201310098

      Thumbnail image of graphical abstract

      Wiley-VCH, Weinheim, 2013. 828 pp., hardcover, € 139.00.—ISBN 978-3527333912

    2. Drug Delivery in Oncology. From Basic Research to Cancer Therapy. 3 Volumes. Edited by Felix Kratz, Peter Senter and Henning Steinhagen. (pages 3547–3548)

      Daria Y. Alakhova and Alexander Y. Kabanov

      Version of Record online: 6 FEB 2014 | DOI: 10.1002/anie.201309567

      Thumbnail image of graphical abstract

      Wiley-VCH, Weinheim, 2011. 1690 pp., hardcover, € 449.00.—ISBN 978-3527328239

  8. Highlight

    1. Top of page
    2. Cover Pictures
    3. Graphical Abstract
    4. News
    5. Author Profile
    6. News
    7. Obituary
    8. Book Reviews
    9. Highlight
    10. Minireview
    11. Review
    12. Communications
    1. Divalent Lanthanides and Uranium

      All the Lanthanides Do It and Even Uranium Does Oxidation State +2 (pages 3550–3551)

      Prof. Dr. Gerd Meyer

      Version of Record online: 11 MAR 2014 | DOI: 10.1002/anie.201311325

      Thumbnail image of graphical abstract

      It takes two to tango: The “reduced”, divalent lanthanides M2+ have electronic ground-state configurations of either 4fn+15d0 (blue) or 4fn5d1 (red). The latter may be incorporated in the spacious anions [M(Cp′)3] and thus the single d1 trapped in a z2 like SOMO. This chemistry has now been transcribed to U2+ (5f36d1), a much sought-after species.

  9. Minireview

    1. Top of page
    2. Cover Pictures
    3. Graphical Abstract
    4. News
    5. Author Profile
    6. News
    7. Obituary
    8. Book Reviews
    9. Highlight
    10. Minireview
    11. Review
    12. Communications
    1. Synthetic Methods

      Metal-Free Hydrogenation of Unsaturated Hydrocarbons Employing Molecular Hydrogen (pages 3552–3557)

      Priv.-Doz. Dr. Jan Paradies

      Version of Record online: 12 FEB 2014 | DOI: 10.1002/anie.201309253

      Thumbnail image of graphical abstract

      Recent metal-free approaches to the hydrogenation of nonpolar double and triple bonds using molecular hydrogen are described. Despite transition-metal-based methodologies for these fundamental chemical transformations, metal-free alternatives are highly desirable. Such technology has only been recently introduced with the aid of frustrated Lewis pairs.

  10. Review

    1. Top of page
    2. Cover Pictures
    3. Graphical Abstract
    4. News
    5. Author Profile
    6. News
    7. Obituary
    8. Book Reviews
    9. Highlight
    10. Minireview
    11. Review
    12. Communications
    1. Electrochemistry

      Electrochemistry of Nanoparticles (pages 3558–3586)

      Steven E. F. Kleijn, Dr. Stanley C. S. Lai, Prof. Dr. Marc T. M. Koper and Prof. Dr. Patrick R. Unwin

      Version of Record online: 26 FEB 2014 | DOI: 10.1002/anie.201306828

      Thumbnail image of graphical abstract

      Revealing electrochemistry: Key issues related to the electrochemistry of nanoparticles are being uncovered through innovative techniques capable of relating activity and structure, ultimately at the level of a single nanoparticle. Recent advances in experimental approaches are discussed and assessed, with particular emphasis on those that enhance the fundamental understanding of electrocatalysis and nanoscale electrochemistry.

  11. Communications

    1. Top of page
    2. Cover Pictures
    3. Graphical Abstract
    4. News
    5. Author Profile
    6. News
    7. Obituary
    8. Book Reviews
    9. Highlight
    10. Minireview
    11. Review
    12. Communications
    1. Graphene Oxides

      Ozonated Graphene Oxide Film as a Proton-Exchange Membrane (pages 3588–3593)

      Dr. Wei Gao, Dr. Gang Wu, Dr. Michael T. Janicke, Dr. David A. Cullen, Dr. Rangachary Mukundan, Jon K. Baldwin, Dr. Eric L. Brosha, Charudatta Galande, Prof. Pulickel M. Ajayan, Dr. Karren L. More, Dr. Andrew M. Dattelbaum and Dr. Piotr Zelenay

      Version of Record online: 14 FEB 2014 | DOI: 10.1002/anie.201310908

      Thumbnail image of graphical abstract

      Oxidized: The reaction of graphene oxide (GO) with ozone results in a high level of oxidation that leads to a significantly improved ionic (protonic) conductivity of GO. This effect originates from enhanced proton hopping, which is due to the higher content of oxygenated functional groups in the basal planes and edges of the ozonated GO as well as the morphology changes that are caused by the ozonation.

    2. Protein–Protein Interactions

      A Multifaceted Secondary Structure Mimic Based On Piperidine-piperidinones (pages 3594–3598)

      Dongyue Xin, Dr. Lisa M. Perez, Prof. Thomas R. Ioerger and Prof. Kevin Burgess

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201400927

      Thumbnail image of graphical abstract

      Do we know, when designing a new peptidomimetic scaffold like the one shown, how it can resemble secondary structures? Design and modular synthesis of this elongated mimic is reported, and the structure is related to ideal and real structures at PPI interfaces.

    3. Superconductors

      Superconducting Double Perovskite Bismuth Oxide Prepared by a Low-Temperature Hydrothermal Reaction (pages 3599–3603)

      Mirza H. K. Rubel, Prof. Akira Miura, Prof. Takahiro Takei, Prof. Nobuhiro Kumada, M. Mozahar Ali, Prof. Masanori Nagao, Prof. Satoshi Watauchi, Prof. Isao Tanaka, Prof. Kengo Oka, Prof. Masaki Azuma, Prof. Eisuke Magome, Prof. Chikako Moriyoshi, Prof. Yoshihiro Kuroiwa and Prof. A. K. M. Azharul Islam

      Version of Record online: 26 FEB 2014 | DOI: 10.1002/anie.201400607

      Thumbnail image of graphical abstract

      A double helping: The title compound was prepared by hydrothermal reaction of NaBiO3n H2O, Ba(OH)2⋅8 H2O, and KOH at 220 °C. The structure of the double perovskite was determined to be (Na0.25K0.45)(Ba1.00)3(Bi1.00)4O12, and thermally decomposed to a simple perovskite structure above 400 °C. The synthesized compounds exhibit superconductive diamagnetism, and zero resistivity below 8 K.

    4. Transformable Capsules

      Selective Host–Guest Interactions of a Transformable Coordination Capsule/Tube with Fullerenes (pages 3604–3607)

      Norifumi Kishi, Prof. Dr. Munetaka Akita and Dr. Michito Yoshizawa

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201311251

      Thumbnail image of graphical abstract

      Varying degrees of hospitality: An M2L4 coordination capsule and an M2L2 coordination tube formed from HgII hinges and bent bispyridine ligands underwent reversible interconversion at room temperature in response to changes in the metal-to-ligand ratio (see picture). Only the capsule accommodated large spherical molecules, fullerenes C60 and C70, and the bound guests were released upon transformation into the tube by the addition of metal ions.

    5. Mesoporous Vanadoborates

      Construction of Mesoporous Frameworks with Vanadoborate Clusters (pages 3608–3611)

      Hong Chen, Dr. Zheng-Bao Yu, Dr. Zoltán Bacsik, Huishuang Zhao, Dr. Qingxia Yao and Prof. Junliang Sun

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201311122

      Thumbnail image of graphical abstract

      Pores for thought: A vanadoborate with a 38×38×20-ring channel system and a mesoporous pore size (24.7×12.7 Å) has been assembled from zinc-containing elliptical vanadoborate clusters and Zn polyhedra (see picture). CO2 adsorption studies confirmed the porosity of the as-synthesized material. This structure demonstrates the possibility of constructing 3D ordered mesopores from inorganic cluster compounds.

    6. Porous Materials

      Pumping through Porous Hydrophobic/Oleophilic Materials: An Alternative Technology for Oil Spill Remediation (pages 3612–3616)

      Jin Ge, Yin-Dong Ye, Hong-Bin Yao, Xi Zhu, Xu Wang, Liang Wu, Jin-Long Wang, Prof. Hang Ding, Prof. Ni Yong, Prof. Ling-Hui He and Prof. Dr. Shu-Hong Yu

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201310151

      Thumbnail image of graphical abstract

      Thirsty, thirsty PHOMs: The continuous collection of oil spills in situ from the surface of water can be accomplished through external pumping on porous hydrophobic/oleophilic materials (PHOMs). Based on this novel design, oil/water separation and oil collection can be simultaneously achieved, and the oil sorption capacity is no longer limited to the volume and weight of the sorption material.

    7. Hydrogel Self-Assembly

      Redox-Responsive Macroscopic Gel Assembly Based on Discrete Dual Interactions (pages 3617–3621)

      Masaki Nakahata, Dr. Yoshinori Takashima and Prof. Dr. Akira Harada

      Version of Record online: 5 MAR 2014 | DOI: 10.1002/anie.201310295

      Thumbnail image of graphical abstract

      Changing partner on cue: The interaction between poly(acrylamide)-based hydrogels modified with β-cyclodextrin (βCD gel), ferrocene (Fc gel), and sodium p-styrenesulfonate (SSNa gel) was investigated. The βCD gel and the Fc gel selectively assembled with one another through a host–guest interaction (see picture). On the other hand, when Fc was oxidized to Fc+, the Fc+ gel selectively adhered to the SSNa gel through a cation–anion interaction.

    8. Molecular Devices

      You have full text access to this OnlineOpen article
      Modification of Fluorescent Photoinduced Electron Transfer (PET) Sensors/Switches To Produce Molecular Photo-Ionic Triode Action (pages 3622–3625)

      Dr. Allen J. M. Huxley, Dr. Marc Schroeder, Dr. H. Q. Nimal Gunaratne and Prof. Dr. A. Prasanna de Silva

      Version of Record online: 26 FEB 2014 | DOI: 10.1002/anie.201310939

      Thumbnail image of graphical abstract

      Making the switch: A fluorophore-spacer1-receptor1-spacer2-receptor2 system has been developed that shows ionically tunable proton-induced off-on switching of fluorescence, reminiscent of thermionic triode behavior. The three-electrode concept of the triode is also followed in the photo-ionic system by the use of three active units within the structure (see picture).

    9. Reaction Mechanisms

      Ruthenium-Catalyzed trans-Selective Hydrostannation of Alkynes (pages 3626–3630)

      M. Sc. Stephan M. Rummelt and Prof. Alois Fürstner

      Version of Record online: 26 FEB 2014 | DOI: 10.1002/anie.201311080

      Thumbnail image of graphical abstract

      Unorthodox: Ruthenium catalysts allow stannanes to be added in a trans fashion across the triple bonds of terminal, internal, silylated, and chlorinated alkynes. This pattern violates the basic mechanism of transition-metal catalysis which otherwise secures high cis selectivity in hydrometalations. Cooperative effects between the ruthenium species and protic functionality render reactions of unsymmetrical substrates regioselective. Cp*=η5-C5Me5.

    10. Solid Polymer Electrolytes

      Transferring Lithium Ions in Nanochannels: A PEO/Li+ Solid Polymer Electrolyte Design (pages 3631–3635)

      Ling-Yun Yang, Da-Xiu Wei, Min Xu, Prof. Ye-Feng Yao and Prof. Qun Chen

      Version of Record online: 5 MAR 2014 | DOI: 10.1002/anie.201307423

      Thumbnail image of graphical abstract

      A new category of crystalline polymer electrolyte has been prepared by the supramolecular self-assembly of PEO (see picture, black), α-cyclodextrin (α-CD, blue), and LiAsF6. In this polymer electrolyte, the nanochannels formed by α-CD provide the pathway for the directional motion of Li+ ions (colored spheres, 5 different environments) and at the same time prevent access of the anions by size exclusion, thereby resulting in good separation of the Li+ ions and the anions.

    11. Planar Phosphorus

      Stabilization of a Diphosphagermylene through pπ–pπ Interactions with a Trigonal-Planar Phosphorus Center (pages 3636–3640)

      Dr. Keith Izod, Daniel G. Rayner, Dr. Salima M. El-Hamruni, Dr. Ross W. Harrington and Dr. Ulrich Baisch

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201308002

      Thumbnail image of graphical abstract

      On a plane: An unusual sterically hindered diphosphagermylene (R2P)2Ge has been synthesized (see picture; R=2,6-iPr2C6H3). This compound possesses a trigonal planar phosphorus atom; the planarity is due to extensive delocalization of the phosphorus lone pair into the vacant p-orbital at germanium. DFT calculations indicate that the Ge[BOND]P bond has significant multiple bond character.

    12. Heterogeneous Catalysis

      Geometric Requirements for Hydrocarbon Catalytic Sites on Platinum Surfaces (pages 3641–3644)

      Jie Gao, Dr. Haibo Zhao, Dr. Xiaofang Yang, Dr. Bruce E. Koel and Dr. Simon G. Podkolzin

      Version of Record online: 24 FEB 2014 | DOI: 10.1002/anie.201309043

      Thumbnail image of graphical abstract

      A preferential catalytic mechanism has been identified for the transformation of acetylene to vinylidene on Pt-Sn surfaces. Unlike a direct H shift along the C[BOND]C bond in organometallic compounds, this mechanism requires three adjacent Pt atoms. The same requirement is identified for C[BOND]H bond cleavage. Without three-fold Pt sites, the reaction mechanism changes, and reactions of H transfer and C[BOND]H bond cleavage are suppressed.

    13. Nanosheet Exfoliation

      One-Step Exfoliation and Fluorination of Boron Nitride Nanosheets and a Study of Their Magnetic Properties (pages 3645–3649)

      Miao Du, Xianlei Li, Aizhu Wang, Prof. Yongzhong Wu, Prof. Xiaopeng Hao and Prof. Mingwen Zhao

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201308294

      Thumbnail image of graphical abstract

      Wafer-thin and mint condition: Fluorinated hexagonal boron nitride nanosheets (F-BNNSs) can be prepared by using ammonium fluoride to exfoliate and fluorinate hexagonal boron nitride. The as-prepared products can exhibit ferromagnetic characteristics at room temperature, which would have good potential applications in spintronic devices.

    14. Peptidomimetics

      Diphenylacetylene-Linked Peptide Strands Induce Bidirectional β-Sheet Formation (pages 3650–3653)

      Dr. Hannah Lingard, Jeongmin T. Han, Dr. Amber L. Thompson, Dr. Ivanhoe K. H. Leung, Dr. Richard T. W. Scott, Dr. Sam Thompson and Prof. Andrew D. Hamilton

      Version of Record online: 19 FEB 2014 | DOI: 10.1002/anie.201309353

      Thumbnail image of graphical abstract

      The importance of β-sheet structures at the interface of protein–protein interactions has prompted the development of a range of synthetic strategies to template and stabilize this secondary structural motif. A tetrasubstituted diphenylacetylene is examined as a central nucleating point for the projection of extended sheet structures in two directions.

    15. Surface Chemistry

      Controlled Carbon Nitride Growth on Surfaces for Hydrogen Evolution Electrodes (pages 3654–3658)

      Dr. Menny Shalom, Dr. Sixto Gimenez, Florian Schipper, Isaac Herraiz-Cardona, Prof. Juan Bisquert and Prof. Dr. Markus Antonietti

      Version of Record online: 26 FEB 2014 | DOI: 10.1002/anie.201309415

      Thumbnail image of graphical abstract

      A scoff at non-nobles: The reduction of water to hydrogen using a metal-free carbon nitride (C3N4) electrocatalyst in neutral and alkaline environments is demonstrated. An efficient, easy, and general method for growing ordered carbon nitride on different electrodes was developed. The metal-free catalyst demonstrates low overpotential values, which are comparable to non-noble metals, with reasonable current densities.

    16. Substrate Recognition

      Switching Demethylation Activities between AlkB Family RNA/DNA Demethylases through Exchange of Active-Site Residues (pages 3659–3662)

      Chenxu Zhu and Prof. Chengqi Yi

      Version of Record online: 5 MAR 2014 | DOI: 10.1002/anie.201310050

      Thumbnail image of graphical abstract

      Exchange program: Divergent active-site residues contribute to the substrate recognition and demethylation specificity of RNA/DNA demethylases AlkB, FTO, and ALKBH5. Swapping these residues results in partially switched demethylation activities (see picture). In the implicated inhibitor design principle, such divergent active-site sequences could aid the design of selective inhibitors that discriminate these demethylases.

    17. Far-IR Spectroscopy

      Gas-Phase Peptide Structures Unraveled by Far-IR Spectroscopy: Combining IR-UV Ion-Dip Experiments with Born–Oppenheimer Molecular Dynamics Simulations (pages 3663–3666)

      Sander Jaeqx, Prof. Dr. Jos Oomens, Dr. Alvaro Cimas, Prof. Dr. Marie-Pierre Gaigeot and Dr. Anouk M. Rijs

      Version of Record online: 26 FEB 2014 | DOI: 10.1002/anie.201311189

      Thumbnail image of graphical abstract

      The use of low-frequency modes (towards 100 cm−1) for structural assignment of peptides is explored. This far-IR region possibly contains detailed information on the secondary structure. The use of Born–Oppenheimer molecular dynamics simulations is discussed to calculate the far-IR signature of peptides.

    18. Nanoparticles

      In Situ Total X-Ray Scattering Study of WO3 Nanoparticle Formation under Hydrothermal Conditions (pages 3667–3670)

      Dr. Dipankar Saha, Dr. Kirsten M. Ø. Jensen, Dr. Christoffer Tyrsted, Espen D. Bøjesen, Dr. Aref Hasen Mamakhel, Dr. Ann-Christin Dippel, Dr. Mogens Christensen and Prof. Dr. Bo B. Iversen

      Version of Record online: 26 FEB 2014 | DOI: 10.1002/anie.201311254

      Thumbnail image of graphical abstract

      Hard facts about solution species: Nanoparticles of WO3 crystallize from a complex precursor structure, as shown by in situ total scattering. The precursor structure exists in solution.

    19. In Situ Imaging

      Click-Assembled, Oxygen-Sensing Nanoconjugates for Depth-Resolved, Near-Infrared Imaging in a 3 D Cancer Model (pages 3671–3674)

      Alexander J. Nichols, Dr. Emmanuel Roussakis, Oliver J. Klein and Prof. Dr. Conor L. Evans

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201311303

      Thumbnail image of graphical abstract

      Embracing the CAOS: A click-assembled oxygen-sensing (CAOS) nanoconjugate was developed for studying oxygenation in complex tissue regions. Click-based ligation of preassembled subunits (shown as colored segments) was used to create tissue-penetrating near-infrared-emissive molecular probes, which enable oxygen-sensitive imaging within a 3D tumor spheroid model through the use of confocal phosphorescence microscopy.

    20. Electrocatalysis

      Hollow Spheres of Iron Carbide Nanoparticles Encased in Graphitic Layers as Oxygen Reduction Catalysts (pages 3675–3679)

      M.Sc. Yang Hu, Dr. Jens Oluf Jensen, Dr. Wei Zhang, Dr. Lars N. Cleemann, Prof. Wei Xing, Prof. Niels J. Bjerrum and Dr. Qingfeng Li

      Version of Record online: 19 FEB 2014 | DOI: 10.1002/anie.201400358

      Thumbnail image of graphical abstract

      Oxygen reduction: Hollow spheres comprising uniform iron carbide (Fe3C) nanoparticles encased by graphitic layers were synthesized (see picture). The spheres show excellent electrocatalytic activity and high stability in both acidic and alkaline media for the oxygen reduction reaction. A synergistic mechanism is proposed.

    21. Carbon

      Diamond: Electronic Ground State of Carbon at Temperatures Approaching 0 K (pages 3680–3683)

      Prof. Wojciech Grochala

      Version of Record online: 24 FEB 2014 | DOI: 10.1002/anie.201400131

      Thumbnail image of graphical abstract

      Graphite or diamond? The relative stabilities of graphite and diamond are revisited with hybrid density functional theory calculations. The electronic energy of diamond is computed to be more negative by 1.1 kJ mol−1 than that of graphite at a temperature of 0 K and in the absence of an external pressure.

    22. Kinetic Resolution

      Highly Enantioselective Kinetic Resolution of Axially Chiral BINAM Derivatives Catalyzed by a Brønsted Acid (pages 3684–3687)

      Dr. Dao-Juan Cheng, Liang Yan, Prof. Dr. Shi-Kai Tian, Ming-Yue Wu, Lu-Xin Wang, Zi-Li Fan, Dr. Sheng-Cai Zheng, Prof. Dr. Xin-Yuan Liu and Prof. Dr. Bin Tan

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201310562

      Thumbnail image of graphical abstract

      Chiral BINAMs on demand: A highly efficient strategy for the kinetic resolution of axially chiral BINAM derivatives involving a chiral Brønsted acid catalyzed imine formation and transfer hydrogenation cascade process was developed. The kinetic resolution provides a convenient route to chiral BINAM derivatives in high yields with excellent enantioselectivities.

    23. Asymmetric Catalysis

      Rhodium-Catalyzed Sequential Allylic Amination and Olefin Hydroacylation Reactions: Enantioselective Synthesis of Seven-Membered Nitrogen Heterocycles (pages 3688–3692)

      Jeffrey S. Arnold, Edward T. Mwenda and Prof. Dr. Hien M. Nguyen

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201310354

      Thumbnail image of graphical abstract

      A two-step process has been developed for the formation of enantioenriched seven-membered-ring aza ketones under mild conditions. The approach consists of a rhodium-catalyzed asymmetric amination of allylic trichloroacetimidates with 2-aminobenzaldehydes (C[BOND]N bond) followed by intramolecular hydroacylation (C[BOND]C bond) of the alkenal products and exhibits broad substrate scope and functional-group tolerance (see example).

    24. Synthetic Methods

      Chemo- and Regioselective C(sp3)[BOND]H Arylation of Unactivated Allylarenes by Deprotonative Cross-Coupling (pages 3693–3697)

      Nusrah Hussain, Gustavo Frensch, Jiadi Zhang and Prof. Patrick J. Walsh

      Version of Record online: 26 FEB 2014 | DOI: 10.1002/anie.201309084

      Thumbnail image of graphical abstract

      Basic chemoselectivity: Combination of aryl bromides, allylbenzene, base, and a palladium catalyst usually results in a Heck coupling reaction. With the same reagents, the Heck reaction can be circumvented when a strong base is used. While the base controls the chemoselectivity, the catalyst handles the regiochemistry, affording 1,1-diarylprop-2-enes that are inaccessible by the Heck pathway (see scheme; DCCP=deprotonative cross-coupling process).

    25. Gas Adsorption

      Supercapacitive Swing Adsorption of Carbon Dioxide (pages 3698–3701)

      Berenika Kokoszka, Nina K. Jarrah, Cong Liu, Prof. Dr. David T. Moore and Prof. Dr. Kai Landskron

      Version of Record online: 24 FEB 2014 | DOI: 10.1002/anie.201310308

      Thumbnail image of graphical abstract

      A new electrical effect, the so-called supercapacitive swing adsorption (SSA) effect, is reported for the first time. SSA enabled the reversible and selective adsorption and desorption of carbon dioxide by the capacitive charge and discharge of porous carbon materials.

    26. Carborane Conjugation

      You have full text access to this OnlineOpen article
      Crystal Structures of the Carborane Dianions [1,4-(PhCB10H10C)2C6H4]2− and [1,4-(PhCB10H10C)2C6F4]2− and the Stabilizing Role of the para-Phenylene Unit on 2 n+3 Skeletal Electron Clusters (pages 3702–3705)

      Dr. Jan Kahlert, Dr. Hans-Georg Stammler, Beate Neumann, Dr. Rachel A. Harder, Prof. Dr. Lothar Weber and Dr. Mark A. Fox

      Version of Record online: 26 FEB 2014 | DOI: 10.1002/anie.201310718

      Thumbnail image of graphical abstract

      Reduction of two­ ortho-carboranyl-benzenes (see scheme) reversibly lead to the formation of stable, diamagnetic dianions which were isolated as tris(dimethoxyethane) sodium salts and characterized by X-ray crystallography and NMR spectroscopy. Both clusters in these dianions possess an unusual 2 n+3 skeletal electron count and are stabilized by π conjugation with the para-phenylene unit.

    27. Homogeneous Catalysis

      Copper-Catalyzed Site-Selective Intramolecular Amidation of Unactivated C(sp3)[BOND]H Bonds (pages 3706–3710)

      Dr. Xuesong Wu, Yan Zhao, Dr. Guangwu Zhang and Prof. Dr. Haibo Ge

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201311263

      Thumbnail image of graphical abstract

      Getting ahead on tams: The intramolecular dehydrogenative amidation of aliphatic amides, directed by a bidentate ligand, was developed using a copper-catalyzed sp3 C[BOND]H bond functionalization process to deliver β-lactams. The reaction favors the C[BOND]H bonds of β-methyl groups over the unactivated methylene C[BOND]H bonds, as well as aromatic C(sp2)[BOND]H bonds and unactivated secondary C(sp3)[BOND]H bonds of rings.

      Corrected by:

      Corrigendum: Corrigendum: Copper-Catalyzed Site-Selective Intramolecular Amidation of Unactivated C(sp3)[BOND]H Bonds

      Vol. 54, Issue 9, 2584, Version of Record online: 17 FEB 2015

    28. Hollow Nanostructures

      Formation of NixCo3−xS4 Hollow Nanoprisms with Enhanced Pseudocapacitive Properties (pages 3711–3714)

      Le Yu, Dr. Lei Zhang, Hao Bin Wu and Prof. Xiong Wen (David) Lou

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201400226

      Thumbnail image of graphical abstract

      NiCo in prism: Uniform hollow NixCo3−xS4 prisms with a tunable composition can be facilely synthesized through an efficient self-templating conversion method. Benefiting from the unique structural and compositional features, the as-obtained NixCo3−xS4 hollow prisms show excellent electrochemical performance as electrode materials for supercapacitors.

    29. Gold Catalysis

      Synthesis of Highly Substituted 3-Formylfurans by a Gold(I)-Catalyzed Oxidation/1,2-Alkynyl Migration/Cyclization Cascade (pages 3715–3719)

      M. Sc. Tao Wang, M. Sc. Shuai Shi, M. Sc. Max M. Hansmann, Dipl.-Chem. Eva Rettenmeier, Dr. Matthias Rudolph and Prof. Dr. A. Stephen K. Hashmi

      Version of Record online: 24 FEB 2014 | DOI: 10.1002/anie.201310146

      Thumbnail image of graphical abstract

      Blazing a new trail: 3-Formylfurans were prepared by a gold(I)-catalyzed cascade reaction that involves oxidation, 1,2-alkynyl migration, and cyclization from simple, easily available 1,4-diyn-3-ols. Isotope-labeling experiments and DFT calculations were carried out to elucidate the reaction mechanism.

    30. Superacid Systems

      The Existence of Hexafluoroarsenic(V) Acid (pages 3720–3721)

      Dr. Joachim Axhausen, Dr. Karin Lux and Prof. Dr. Andreas Kornath

      Version of Record online: 20 JAN 2014 | DOI: 10.1002/anie.201308023

      Thumbnail image of graphical abstract

      An unexpected encounter: The protonation of trimethylsilyl-N,N-dimethylcarbamate in the superacid media HF/AsF5 leads under certain conditions, in addition to dimethyl ammoniumhexafluoridoarsenate [Me2NH2]+[AsF6], to the hexafluoroarsenic(V) acid HAsF6.

    31. Hydrogenations

      Heteroatom-Free Arene-Cobalt and Arene-Iron Catalysts for Hydrogenations (pages 3722–3726)

      M. Sc. Dominik Gärtner, Dr. Alice Welther, Dr. Babak Rezaei Rad, Prof. Dr. Robert Wolf and Prof. Dr. Axel Jacobi von Wangelin

      Version of Record online: 24 FEB 2014 | DOI: 10.1002/anie.201308967

      Thumbnail image of graphical abstract

      Especially high selectivities were observed in the hydrogenation of various alkenes, ketones, and imines with bis(anthracene)cobaltate(−I) [K(dme)2{Co(C14H10)2}] under mild conditions (1–5 mol % cat., 1–10 bar H2, 20–60 °C). Mechanistic studies indicate the operation in alkene hydrogenations of a homogeneous catalyst formed by initial ligand exchange and stabilized by the coordination of π-acidic alkenes or arenes.

    32. Main-Group Chemistry

      Cationic Chains of Phosphanyl- and Arsanylboranes (pages 3727–3730)

      Christian Marquardt, Dr. Christine Thoms, Andreas Stauber, Dr. Gábor Balázs, Dr. Michael Bodensteiner and Prof. Dr. Manfred Scheer

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201310519

      Thumbnail image of graphical abstract

      Inorganic alkanes: The monomeric Group 13/15 building blocks H2EBH2⋅NMe3 (E=P, As) have been linked to form cationic chains in a straightforward synthesis in good yields. The backbone consists of alternating B and P or As atoms bearing only hydrogen substituents. DFT calculations give insight into the formation, the bonding situation, and also the structural parameters of the cationic inorganic alkanes.

    33. Redox Deracemization

      You have full text access to this OnlineOpen article
      Deracemization By Simultaneous Bio-oxidative Kinetic Resolution and Stereoinversion (pages 3731–3734)

      Dr. Joerg H. Schrittwieser, Dr. Bas Groenendaal, Dr. Verena Resch, Dr. Diego Ghislieri, Dr. Silvia Wallner, Eva-Maria Fischereder, Elisabeth Fuchs, Barbara Grischek, Dr. Johann H. Sattler, Prof. Dr. Peter Macheroux, Prof. Dr. Nicholas J. Turner and Prof. Dr. Wolfgang Kroutil

      Version of Record online: 24 FEB 2014 | DOI: 10.1002/anie.201400027

      Thumbnail image of graphical abstract

      From two make one: Chemo-enzymatic stereoinversion and enzymatic kinetic resolution have been combined in a simultaneous cascade process to transform racemic substrates (A, ent-A) into optically pure product P. The concept was exemplified for benzylisoquinolines rac-1 yielding optically pure berbines (S)-2. The reaction system comprised a monoamine oxidase (MAO-N), morpholine-borane, and the berberine bridge enzyme (BBE).

    34. Tailor-Made Peptide Inhibitors

      Harnessing the Evolvability of Tricyclic Microviridins To Dissect Protease–Inhibitor Interactions (pages 3735–3738)

      Dr. Annika R. Weiz, Dr. Keishi Ishida, Felix Quitterer, Sabine Meyer, Dr. Jan-Christoph Kehr, Prof. Dr. Kristian M. Müller, Prof. Dr. Michael Groll, Prof. Dr. Christian Hertweck and Prof. Dr. Elke Dittmann

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201309721

      Thumbnail image of graphical abstract

      An expression platform for ribosomally produced tricyclic microviridins provides fundamental insights into protease–inhibitor interactions and sets the stage for the tailor-made design of peptides selectively targeting different serine-type proteases. The complex structure of trypsin and microviridin J uncovers the intimate protease–inhibitor interactions.

    35. Self-Assembly

      A New Structural Motif for an Enantiomerically Pure Metallosupramolecular Pd4L8 Aggregate by Anion Templating (pages 3739–3742)

      M. Sc. Christoph Klein, Dr. Christoph Gütz, Maximilian Bogner, M. Sc. Filip Topić, Prof. Dr. Kari Rissanen and Prof. Dr. Arne Lützen

      Version of Record online: 3 MAR 2014 | DOI: 10.1002/anie.201400626

      Thumbnail image of graphical abstract

      Close association: A BINOL-based bis(3-pyridyl) ligand assembles into a [Pd4L8] complex upon coordination to PdII ions. The formation of the aggregate is templated by two BF4 ions that are encapsulated in peripheral cavities. The palladium ions are arranged in a distorted tetrahedral fashion, which forces the ligand to adopt two different conformations (see picture).

    36. Reactions of [5]Cumulenes

      Unexpected Formation of a [4]Radialene and Dendralenes by Addition of Tetracyanoethylene to a Tetraaryl[5]cumulene (pages 3743–3747)

      Johanna A. Januszewski, Dr. Frank Hampel, Dr. Christian Neiss, Prof. Dr. Andreas Görling and Prof. Dr. Rik R. Tykwinski

      Version of Record online: 26 FEB 2014 | DOI: 10.1002/anie.201309355

      Thumbnail image of graphical abstract

      Unusual structures and interesting electronic properties characterize the cyclic products from the reaction of TCNE with tetraaryl[5]cumulene. Mechanistic investigations, aided by DFT calculations, outline a likely pathway to the observed products. The addition of MeOH, EtOH, and Br2 to various intermediates leads to the interesting dendralene compounds.

SEARCH

SEARCH BY CITATION