• 1
    Morimoto C, Letvin NL, Distaso JA, Aldrich WR, Schlossman SF: The isolation and characterization of the human suppressor inducer T cell subset. J Immunol 134: 15081515, 1985
  • 2
    Letvin NL, Morimoto C, Aldrich WR, Schlossman SF: Definition of the T-lymphocyte inducer of suppression in primates using a monoclonal antibody. Cell Immunol 94: 360368, 1985
  • 3
    Morimoto C, Letvin NL, Distaso JA, Brown HM, Schlossman SF: The cellular basis for the induction of antigen specific T8 suppressor cells. Eur J Immunol 16: 198204, 1986
  • 4
    Morimoto C, Matsuyama T, Rudd CE, Forsgren A, Letvin NL, Schlossman SF: Role of the 2H4 molecule in the activation of suppressor inducer function. Eur J Immunol 18: 731737, 1988
  • 5
    Morimoto C, Reinherz EL, Borel Y, Mantzouranis E, Steinberg AD, Schlossman SF: An autoantibody to an immunoregulatory inducer population in patients with juvenile rheumatoid arthritis. J Clin Invest 67: 753761, 1981
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    Morimoto C, Reinherz EL, Borel Y, Schlossman SF: Direct demonstration of the human suppressor inducer subset by anti-T cell antibodies. J Immunol 130: 157161, 1983
  • 7
    Takeuchi T, Tanaka S, Steinberg AD, Matsuyama T, Schlossman SF, Morimoto C: Defective expression of the 2H4 molecule after autologous mixed lymphocyte reaction activation in systemic lupus erythematosus patients. J Clin Invest 82: 12881294, 1988
  • 8
    Rudd CE, Morimoto C, Wong LL, Schlossman SF: The structure of the 2H4 antigen: a subset of the LCA/T200 family of antigens involved in immune suppression, Leukocyte Typing III. Edited by AJMcMichael, PCLBeverley, SCobbold, MJCrumpton. Oxford, Oxford University Press, 1987
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    Koffler D: Immunopathogenesis of systemic lupus erythematosus. Annu Rev Med 25: 149164, 1974
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    Morimoto C, Schlossman SF: Antilymphocyte antibodies and systemic lupus erythematosus. Arthritis Rheum 30: 225228, 1987
  • 11
    Winfield JB: Anti-lymphocyte antibodies in systemic lupus erythematosus. Clin Rheum Dis 11: 523549, 1985
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    Morimoto C, Steinberg AD, Letvin NL, Hagan M, Takeuchi T, Daley J, Levine H, Schlossman SF: A defect of immunoregulatory T cell subsets in systemic lupus erythematosus patients demonstrated with anti-2H4 antibody. J Clin Invest 79: 762768, 1987
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    Abdou NI, Sagawa A, Rascual E, Habert J, Sadeghee S: Suppressor T cell abnormality in idiopathic systemic lupus erythematosus. Clin Immunol Immunopathol 6: 192199, 1976
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    Bresnihan B, Jasin HE: Suppressor function of peripheral blood mononuclear cells in normal individuals and patients with systemic lupus erythematosus. J Clin Invest 59: 106116, 1977
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    Morimoto C: Loss of suppressor T-lymphocyte function in patients with systemic lupus erythematosus (SLE). Clin Exp Immunol 32: 125133, 1978
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    Sakane T, Steinberg AD, Green I: Studies of immune functions of patients with systemic lupus erythematosus. I. Dysfunction of suppressor T-cell activity related to impaired generation of, rather than response to, suppressor cells. Arthritis Rheum 21: 657664, 1978
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    Morimoto C, Abe T, Toguchi T, Kiyotaki M, Homma M: Studies of anti-lymphocyte antibody of patients with active SLE. I. Cause of loss of suppressor T lymphocyte function. Scand J Immunol 10: 213221, 1979
  • 18
    Sagawa A, Abdou NI: Suppressor cell antibody in systemic lupus erythematosus: possible mechanism for suppressor cell dysfunction. J Clin Invest 63: 536539, 1979
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    Sakane T, Steinberg AD, Reeves JP, Green I: Studies of immune functions of patients with systemic lupus erythematosus: complement-dependent immunoglobulin M anti-thymus-derived cell antibodies preferentially inactivate suppressor cells. J Clin Invest 63: 954965, 1979
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    Morimoto C, Reinherz EL, Schlossman SF, Schur PH, Mills JA, Steinberg AD: Alterations in immunoregulatory T cell subsets in active systemic lupus erythematosus. J Clin Invest 66: 11711174, 1980
  • 21
    Morimoto C, Reinherz EL, Abe T, Homma M, Schlossman SF: Characteristics of anti-T cell antibodies in SLE: evidence for selective reactivity with normal suppressor cells defined by monoclonal antibodies. Clin Immunol Immunopathol 16: 474484, 1980
  • 22
    Sakane T, Kotani H, Takada S, Murakawa Y, Ueda Y: A defect in the suppressor circuits among OKT4+ cell populations in patients with systemic lupus erythematosus occurs independently of a defect in the OKT8+ suppressor T cell function. J Immunol 131: 753761, 1983
  • 23
    Morimoto C, Reinherz EL, Distaso JA, Steinberg AD, Schlossman SF: Relationship between systemic lupus erythematosus, T cell subsets, anti-T cell antibodies and T cell functions. J Clin Invest 73: 689700, 1984
  • 24
    Winfield JB, Shaw M, Yamada A, Minota S: Subset specificity of antilymphocyte antibodies in systemic lupus erythematosus. II. Preferential reactivity with T4+ cells is associated with relative depletion of autologous T4+ cells. Arthritis Rheum 30: 162168, 1987
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    Yamada A, Cohen PL, Winfield JB: Subset specificity of antilymphocyte antibodies in systemic lupus erythematosus: preferential reactivity with cells bearing the T4 and autologous erythrocyte receptor phenotypes. Arthritis Rheum 28: 262270, 1985
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    Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, Schaller JG, Talal N, Winchester RJ: The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25: 12711277, 1982
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    Blaese RM, Grayson J, Steinberg AD: Increased immunoglobulin-secreting cells in the blood of patients with active systemic lupus erythematosus. Am J Med 69: 345350, 1980
  • 28
    Reinherz EL, Schlossman SF: The differentiation and function of human T lymphocytes. Cell 19: 821827, 1980
  • 29
    Winfield JB, Winchester RJ, Wernet P, Fu SM, Kunkel HG: Nature of cold-reactive antibodies to lymphocyte surface determinants in systemic lupus erythematosus. Arthritis Rheum 18: 18, 1975
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    Winfield JB, Winchester RJ, Kunkel HG: Association of cold-reactive antilymphocyte antibodies with lymphopenia in systemic lupus erythematosus. Arthritis Rheum 18: 587594, 1975
  • 31
    Streuli M, Matsuyama T, Morimoto C, Schlossman SF, Saito H: Identification of the sequence required for expression of the 2H4-epitope on the human leukocyte common antigens. J Exp Med 166: 15671572, 1987
  • 32
    Smolen JS, Chused TM, Leiserson WM, Reeves JP, Alling D, Steinberg AD: Heterogeneity of immunoregulatory T-cell subsets in systemic lupus erythematosus: correlation with clinical features. Am J Med 72: 783790, 1982
  • 33
    Smolen JS, Morimoto C, Steinberg AD, Wolf A, Schlossman SF, Steinberg RT, Penne E, Reinherz EL, Reichlin M, Chused TM: Systemic lupus erythematosus: delineation of subpopulations by clinical, serologic and T-cell marker analysis. Am J Med Sci 289: 139147, 1985
  • 34
    Takeuchi T, Rudd CE, Schlossman SF, Morimoto C: Induction of suppression following autologous mixed lymphocyte reaction: role of a novel 2H4 antigen. Eur J Immunol 16: 198204, 1987
  • 35
    Kumagai S, Steinberg AD, Green I: Antibodies to T cells in patients with SLE mediated ADCC against human T cells. J Clin Invest 67: 605614, 1981
  • 36
    Minota S, Winfield JB: Identification of three major target molecules of IgM antilymphocyte autoantibodies in systemic lupus erythematosus. J Immunol 139: 36443651, 1987
  • 37
    Minota S, Winfield JB: IgG anti-lymphocyte antibodies in systemic lupus erythematosus react with surface molecules shared by peripheral T cells and a primitive T cell line. J Immunol 138: 17501756, 1986