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Keywords:

  • conjugated alkynyl cycloalkenones;
  • 3-oxocycloalkenyl triflates;
  • palladium(0) catalyst;
  • silver acetate;
  • Sonogashira–Linstrumelle reaction

Abstract

Palladium—silver acetate-catalyzed cross coupling of vinyl triflates and 1-alkynes was investigated. This strategy offered a very straightforward and efficient method for access to conjugated alkynyl cycloalkenones from the conjugated vinyl triflates and 1-alkynes. Moreover, the triflates derived from 1,3-cycloalkadione needed no further purification and could be reacted immediately with 1-alkynes to provide the conjugated alkynyl cycloalkenones in excellent overall yields. Copyright © 2009 John Wiley & Sons, Ltd.