Applied Organometallic Chemistry

Cover image for Vol. 27 Issue 2

February 2013

Volume 27, Issue 2

Pages i–iii, 69–124

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. Full Papers
    1. Issue Information (pages i–iii)

      Article first published online: 21 JAN 2013 | DOI: 10.1002/aoc.2973

  2. Full Papers

    1. Top of page
    2. Issue Information
    3. Full Papers
    1. Efficient Simmons–Smith cyclopropanation with Zn/Cu and CH2I2 (pages 69–72)

      Kanami Fujii, Kodai Shiine, Tomonori Misaki and Takashi Sugimura

      Article first published online: 21 JAN 2013 | DOI: 10.1002/aoc.2935

      Thumbnail image of graphical abstract

      An appropriate solvent to perform the original Simmons-Smith reaction was reinvestigated. Among available solvents, cyclopentyl methyl ether (CPME) was found to be the best so far studied. Compared with diethyl ether of the commonest solvent, the reaction time to be completed was much shorter. The product yields and selectivities were mostly identical or better in some cases. The good performance of CPME is mainly due to its moderate polarity and high boiling point.

    2. Polycarbosilane-supported titanium(IV) catalyst for Knoevenagel condensation reaction (pages 73–78)

      Kunniyur Mangala and Krishnapillai Sreekumar

      Article first published online: 20 DEC 2012 | DOI: 10.1002/aoc.2941

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      Polycarbosilane (PCS) having highly crosslinked structure and high surface area had been synthesized and Titanium metal ion was attached to it. Knoevenagel condensation reaction catalyzed by titanium incorporated polycarbosilane is reported. Polycarbosilane supported transition metal catalysts have been prepared for the first time and used successfully in Knoevenagel condensation reaction.

    3. Synthesis and characterization of a novel precursor-derived ZrC/ZrB2 ultra-high-temperature ceramic composite (pages 79–84)

      Hao Wang, Xingbo Chen, Bo Gao, Jun Wang, Yingde Wang, Shugang Chen and Yanzi Gou

      Article first published online: 6 DEC 2012 | DOI: 10.1002/aoc.2943

      Thumbnail image of graphical abstract

      ZrC/ZrB2 ceramic composites were prepared from a novel precursor PZCB synthesized by the reaction between Cp2Zr(CH═CH2)2 and borane. The ceramic yield was 50% and the obtained well-distributed ZrC/ZrB2 ceramic composites had very good high-temperature resistance.

    4. Palladium-catalyzed synthesis of 8-allyl or 8-prenylcoumarins by using organotin reagents as multicoupling nucleophiles (pages 85–88)

      Qiang Yin, Han Yan, Yaqin Zhang, Yige Wang, Guojin Zhang, Yuxiang He and Weihua Zhang

      Article first published online: 4 DEC 2012 | DOI: 10.1002/aoc.2944

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      A efficient protocol for synthesis of 8-allyl or 8-prenylcoumarins has been developed using organotin reagents as multicoupling nucleophiles. The cross-coupling reaction proceeded smoothly under mild conditions and permitted the formation of 8-allyl or 8-prenylcoumarin compounds in good yields. Relative to the traditional Claisen rearrangement or free radical approaches to these molecules, the method appears to be higher yielding and more selective

    5. Studies on the nuclease activity and interactions of the mixed-polypyridyl [Ni2(1,3-tpbd)(diimine)2(H2O)2]4+ complexes with thioredoxin reductase (pages 89–97)

      Dong-Dong Li and Hui-Hui Zeng

      Article first published online: 20 DEC 2012 | DOI: 10.1002/aoc.2945

      Thumbnail image of graphical abstract

      Three new nickel (II) complexes display efficiently oxidative cleavage of supercoiled DNA in the presence of H2O2 (250 μM) with 3 exhibiting highest nuclease activity. They also show propensity to react with thioredoxin reductase, the IC50 values are calculated to be 26.54 ± 0.57, 31.03 ± 3.33, and 8.69 ± 2.54 μM, respectively, showing a more marked inhibitory effect on thioredoxin reductase by complex 3 than other two complexes.

    6. Application of ferrocenylimidazolium salts as catalysts for the transfer hydrogenation of ketones (pages 98–108)

      Monisola I. Ikhile, Muhammad D. Bala, Vincent O. Nyamori and J. Catherine Ngila

      Article first published online: 21 JAN 2013 | DOI: 10.1002/aoc.2947

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      Ferrocenylimidazolium salts with methylene and phenyl groups bridging the ferrocenyl and alkylimidazolium moieties were found to be very active catalysts in transforming ketones to the corresponding alcohols with turnover number up to 1880.

    7. Ligand- and solvent-free synthesis of 2-aminobenzothiazoles by copper-catalyzed tandem reaction of 2-haloanilines with isothiocyanates (pages 109–113)

      Ruiya Yao, Haiyi Liu, Yichao Wu and Mingzhong Cai

      Article first published online: 19 DEC 2012 | DOI: 10.1002/aoc.2949

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      An environmentally friendly, efficient and practical method for the synthesis of 2-aminobenzothiazoles has been developed by a copper(II)-catalyzed tandem reaction of 2-haloanilines with isothiocyanates under ligand- and solvent-free conditions in air.

    8. Silyl modification of biologically active compounds. 13. Synthesis, cytotoxicity and antibacterial action of N-methyl-N-(2-triorganylsiloxyethyl)-1,2,3,4-tetrahydro(iso)quinolinium iodides (pages 114–124)

      Alla Zablotskaya, Izolda Segal, Yuris Popelis, Solveiga Grinberga, Irina Shestakova, Vizma Nikolajeva and Daina Eze

      Article first published online: 19 DEC 2012 | DOI: 10.1002/aoc.2952

      Thumbnail image of graphical abstract

      A series of N-methyl-N-(2-triorganylsiloxyethyl)-1,2,3,4-tetrahydro(iso)quinolinium iodides has been synthesized and characterized by 1H, 13C, 29Si NMR and mass-spectroscopy. The biological activity data exhibited enhancement of inhibitory activity against tumour cell lines and almost all the test bacterial/fungal strains in comparison with their 2-hydroxyethyl precursors. Cytotoxicity in microgram range against cancer cell lines HT-1080 and MG-22A was observed for most compounds.

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