Paper presented to the 153rd Meeting, American Chemical Society, Miami Beach, Florida, April 1967.
Article first published online: 9 MAR 2003
Copyright © 1967 John Wiley & Sons, Inc.
Journal of Applied Polymer Science
Volume 11, Issue 10, pages 1991–2000, October 1967
How to Cite
Refojo, M. F. (1967), Polyelectrolyte complexes: Permeability to water and potential uses in ophthalmology. J. Appl. Polym. Sci., 11: 1991–2000. doi: 10.1002/app.1967.070111015
Prod. No. 1604
- Issue published online: 9 MAR 2003
- Article first published online: 9 MAR 2003
- Manuscript Received: 1 FEB 1967
Complexes from poly(vinylbenzyltrimethylammonium chloride) and polystyrene-sulfonate are transparent, water-insoluble materials which offer interesting possibilities in ophthalmology for contact lenses and surgical implants. The permeability to water of a series of neutral polyelectrolyte complex membranes was determined. The measurements were carried out at relatively low pressure gradients (20–900 mm. Hg). The results are in good agreement with previously reported data obtained at higher pressures (6.9 atm. and higher). The refractive index of the complexes was also determined, and apparently a linear relationship exists between the refractive index and the amount of water in the complex: 70% water, nD 1.40; 45% water, nD 1.48; 35% water, nD 1.51. A polyelectrolyte complex membrane 0.09 mm. thick containing 60% water at equilibrium swelling will have a similar permeability to water as the endothelium of the cornea (1.55 × 10−11 cm.3/sec.-dyne) at 35°C. The same membrane, but with a thickness of 0.03 mm., will have a permeability similar to that of the whole corneal stroma (4.9 × 10−11 cm.3/sec.-dyne). At 0.21 mm. thickness the membrane will have a permeability similar to that of the epithelium (0.67 × 10−11 cm.3/sec.-dyne).