We studied alcoholysis of vinyl acetate and itaconic acid (up to 8.5 mol %) copolymers. We obtained the copolymers both by single and continuous addition of the second comoner, and carried out the alcoholysis in methanol and methanol-gasoline medium at temperature 30°C using sodium hydroxide as catalyst. We established that the presence of itaconic sequences in the vinyl acetate polymer chain in an amount of 1.5–2 mol % causes significant reduction in the viscosity of methanol solutions without greatly affecting the molecular weight of the copolymer. The alcoholysis of random copolymers, containing not more than 4 mol % itaconic sequences takes place at a higher rate. The vinyl acetate-vinyl alcohol copolymer, containing groups of itaconic acid has better surface activity. This is more clearly expressed in the case of random copolymers.