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pH-sensitivity of hydrogels based on complex forming chitosan: Polyether interpenetrating polymer network

Authors

  • Kang De Yao,

    Corresponding author
    1. Department of Materials Science and Engineering, Tianjin University (300072), Tianjin, People's Republic of China
    • Department of Materials Science and Engineering, Tianjin University (300072), Tianjin, People's Republic of China
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  • Tao Peng,

    1. Department of Materials Science and Engineering, Tianjin University (300072), Tianjin, People's Republic of China
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  • M. F. A. Goosen,

    1. Department of Chemical Engineering, Queen's University, Kingston Canada K7L 3N6
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  • Ji Mei Min,

    1. National Laboratory of Natural and Biomimetic Drugs, Beijing Medical University, P. O. Box 216, Beijing (100083), People's Republic of China
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  • Yu Yin He

    1. National Laboratory of Natural and Biomimetic Drugs, Beijing Medical University, P. O. Box 216, Beijing (100083), People's Republic of China
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Abstract

This article deals with a novel, semi-interpenetrating polymer network (semi-IPN), composed of crosslinked chitosan (cr-CS) with glutaraldehyde (GA) and polyether. The pH responsibility of swelling data shows that swelling reaches a maximum at pH = 3.19 and a minimum at pH = 13. The concentration of chitosan acetic acid solution, the amount of crosslinking agent, and polyether, have effects on the swelling behavior of the network. Stimulating-response of the semi-IPN, induced by abrupt changes of pH between 1 and 13, is discussed as well. © 1993 John Wiley & Sons, Inc.

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