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Synthesis of intercalated lamellar hydroxyapatite/gelatin nanocomposite for bone substitute application

Authors

  • Guifu Zuo,

    1. Department of Materials Science, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, People's Republic of China
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  • Chao Liu,

    1. Department of Materials Science, School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300130, People's Republic of China
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  • Honglin Luo,

    1. Department of Materials Science, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, People's Republic of China
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  • Fang He,

    1. Department of Materials Science, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, People's Republic of China
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  • Hui Liang,

    1. Department of Materials Science, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, People's Republic of China
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  • Jiehua Wang,

    1. Department of Biotechnology, School of Agriculture and Bioengineering, Tianjin University, Tianjin 300072, People's Republic of China
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  • Yizao Wan

    Corresponding author
    1. Department of Materials Science, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, People's Republic of China
    • Department of Materials Science, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, People's Republic of China
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Abstract

Hydroxyapatite (HAp)/polymer composites have been widely investigated for bone substitute applications in recent years. Inspired by the arrangement of ordered organic and inorganic layers in natural bones and seashells, for the first time a novel intercalated nanocomposite of gelatin and lamellar HAp was prepared via solution intercalation process. X-ray diffraction (XRD) results showed that the basal spacing of HAp lamellas enlarged by 3.0 nm from 3.1 nm to 6.1 nm, indicating that the gelatin molecules had been intercalated into the gallery of lamellar HAp. The microstructures of pure lamellar HAp and intercalated gelatin/HAp nanocomposite were observed by transmission electron microscopy (TEM) analysis. Fourier transform infrared spectroscopy (FT-IR) analysis revealed that there were chemical interactions between gelatin molecules and HAp. Thermogravimetric analysis (TGA) results confirmed that thermal stability of the composites was enhanced. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009

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