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Molecular imprinting micropolymerbeads having cooperative effect of both surfactant and inosine template

Authors

  • Takayuki Kusunoki,

    1. Department of Materials Science and Technology, Nagaoka University of Technology, 1603-1 Kamitomioka, Niigata 940-2188, Nagaoka, Japan
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  • Takaomi Kobayashi

    Corresponding author
    1. Department of Materials Science and Technology, Nagaoka University of Technology, 1603-1 Kamitomioka, Niigata 940-2188, Nagaoka, Japan
    • Department of Materials Science and Technology, Nagaoka University of Technology, 1603-1 Kamitomioka, Niigata 940-2188, Nagaoka, Japan
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Abstract

Molecular imprinted polymer (MIP) microbeads were prepared by emulsion copolymerization of divinylbenzene (DVB) and methacrylic acid (MAA) in the presence of inosine (INO) template and laurylbenzenesulfonic acid (LBSA) as surfactant. The polymerization was carried out at 55°C under ultrasound exposure. The resulting copolymer microbeads, having 0.1–0.4 μm diameter, were observed to have a binding behavior of INO and surfactant to the polymer which was strongly dependent of the bulk pH; for example, at pH 3, 6, and 10 values of binding for INO to the imprinted copolymer were 3.7 μmol/g, 2.1 μmol/g, and 0 μmol/g, respectively. It was found that LBSA surfactant bound to the MIP microbeads similarly depending on pHs. At pH 3, 6, and 10, the LBSA values of binding were 23 μmol/g, 1.3 μmol/g, and 4.8 μmol/g. It was also noted that the surfactant binding was enhanced in the presence of the INO template. This demonstrated that a cooperative binding with the surfactant was cooperatively occurred in the presence of INO. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010

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