Organic-soluble chitosan/polyhydroxybutyrate ultrafine fibers as skin regeneration prepared by electrospinning

Authors

  • Guiping Ma,

    1. State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
    2. Key Lab of Beijing, City on Preparation and Processing of Novel Polymer Materials, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
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  • Dongzhi Yang,

    1. State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
    2. Key Lab of Beijing, City on Preparation and Processing of Novel Polymer Materials, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
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  • Kemin Wang,

    1. State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
    2. Key Lab of Beijing, City on Preparation and Processing of Novel Polymer Materials, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
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  • Jing Han,

    1. State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
    2. Key Lab of Beijing, City on Preparation and Processing of Novel Polymer Materials, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
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  • Shumin Ding,

    1. Department of Chemical Engineering, Jiangsu Polytechnic University, Changzhou 213164, Jiangsu, People's Republic of China
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  • Guoqiang Song,

    1. Department of Chemical Engineering, Jiangsu Polytechnic University, Changzhou 213164, Jiangsu, People's Republic of China
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  • Jun Nie

    Corresponding author
    1. State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
    2. Key Lab of Beijing, City on Preparation and Processing of Novel Polymer Materials, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
    • State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
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Abstract

In the present contribution, the ultrafine fiber membranes of polyhydroxybutyrate (PHB) and organic-soluble chitosan(O-CS) was prepared by electrospinning. The structure and thermal stability were studied by infrared (FTIR) and thermogravimetric analysis (TG). The surface properties of ultrafine fibers were estimated by contact angle measurements using water. The morphology was observed by scanning electron microscopy (SEM). The cytotoxicity assessment with mouse fibroblast cells (L929) was also investigated. Cell culture results showed that it benefits promoting the cell attachment and proliferation. The results showed it could be as tissue engineering for skin regeneration. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010

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