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Keywords:

  • peptides;
  • modification;
  • star polymers;
  • PEGylation

Abstract

PEGylations of polypeptides with a four-arm PEG (polyethylene glycol) in a dilute DMSO solution resulted in a successful conjugation with terminal specificity, which supports an intriguing PEGylation mechanism via conformational and kinetic control. © 2010 Crown in the right of Canada. J Appl Polym Sci, 2010