Preparation of micrometer-sized, multifunctional capsule particles for cosmetic by microsuspension polymerization utilizing the self-assembling of phase separated polymer method

Authors

  • Shiro Nakai,

    Corresponding author
    1. Department of Research and Development, Rohto Research Village Kyoto, Rohto Pharmaceutical Co., Ltd., Kunimidai 6-5-4, Kizugawa City, Kyoto 619-0216, Japan
    • Department of Research and Development, Rohto Research Village Kyoto, Rohto Pharmaceutical Co., Ltd., Kunimidai 6-5-4, Kizugawa City, Kyoto 619-0216, Japan
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  • Mina Akiyoshi,

    1. Department of Research and Development, Rohto Research Village Kyoto, Rohto Pharmaceutical Co., Ltd., Kunimidai 6-5-4, Kizugawa City, Kyoto 619-0216, Japan
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  • Masayoshi Okubo

    Corresponding author
    1. Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, Rokko, Nada, Kobe 657-8501, Japan
    2. Smart Spheres Workshop Co., Ltd., 2-1-214-122, Koyo-Naka, Higashi-Nada, Kobe 658-0032, Japan
    • Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, Rokko, Nada, Kobe 657-8501, Japan
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Abstract

Micrometer-sized polymer particles with encapsulated ultraviolet (UV) absorbent, fluorescent agent, and blue pigment were successfully prepared by microsuspension polymerization utilizing the Self-assembling of Phase Separated Polymer method. The particles were characterized by optical microscope and particle size distribution analysis, and they were evaluated on their usefulness for cosmetic using UV spectrometry, colorimetry, VISIA™ Evolution, and bioassay. The capsule particles had multifunctional properties, which are very attractive in the cosmetic field, especially in whitening, brightening, the improvement of face-texture, and less noticeable pores in face, as well as the protection from UV. Moreover, bioactivities of the particles under the UV irradiation, which were examined with the films prepared from capsule components, revealed not only makeup effect but also the activation of human epidermal keratinocytes. The results suggest the importance of blue light in the field of cosmetics. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013

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