α-cyclodextrin assisted self-assembly of poly(ethylene glycol)-block-poly(N-isopropylacrylamide) in aqueous media

Authors

  • Fanny Yuen,

    1. Department of Chemical Engineering and Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1
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  • Kam Chiu Tam

    Corresponding author
    1. Department of Chemical Engineering and Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1
    • Department of Chemical Engineering and Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1
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Abstract

Poly(ethylene glycol)-block-poly(N-isopropylacrylamide) (PEG-b-PNIPAM) block copolymers were synthesized by atom transfer radical polymerization, and the α-cyclodextrin (α-CD) induced self-assembly characteristics of the system were elucidated. Below the lower critical solution temperature (LCST) of PNIPAM, CD threaded onto the PEG segments and induced micellization to form rod-shaped nanostructures comprising of a PEG/α-CD condensed phase and a PNIPAM shell. Increasing the temperature of system above the LCST caused the PNIPAM segments to collapse, which resulted in the dethreading of the CD. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013

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