SEARCH

SEARCH BY CITATION

Keywords:

  • cyclodextrin;
  • block copolymers;
  • self-assembly;
  • inclusion complexes;
  • atom transfer radical polymerization

Abstract

Poly(ethylene glycol)-block-poly(N-isopropylacrylamide) (PEG-b-PNIPAM) block copolymers were synthesized by atom transfer radical polymerization, and the α-cyclodextrin (α-CD) induced self-assembly characteristics of the system were elucidated. Below the lower critical solution temperature (LCST) of PNIPAM, CD threaded onto the PEG segments and induced micellization to form rod-shaped nanostructures comprising of a PEG/α-CD condensed phase and a PNIPAM shell. Increasing the temperature of system above the LCST caused the PNIPAM segments to collapse, which resulted in the dethreading of the CD. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013