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Antibacterial and anticoagulation properties of polyethylene/geneO-MPC nanocomposites

Authors

  • Suxing Jin,

    1. Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
    2. Jiangsu Engineering Research Center for Biomedical Function Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
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  • Dong Xu,

    1. Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
    2. Jiangsu Engineering Research Center for Biomedical Function Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
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  • Ninglin Zhou,

    Corresponding author
    1. Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
    2. Jiangsu Engineering Research Center for Biomedical Function Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
    • Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
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  • Jiang Yuan,

    Corresponding author
    1. Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
    2. Jiangsu Engineering Research Center for Biomedical Function Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
    • Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
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  • Jian Shen

    1. Jiangsu Key Laboratory of Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
    2. Jiangsu Engineering Research Center for Biomedical Function Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China
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Abstract

Nanocomposite technology has been utilized to improve biocompatibility and mechanical property of biomedical catheter materials. In this study, graphene oxide (GeneO), graphene oxide complexes with 2-(methacryloyloxy)ethyl phosphorylcholine (GeneO-MPC), and modified polyethylene (PE/GeneO-MPC) nanocomposites applied in biomedical catheter materials field were synthesized and their bacteriostasis to E. coli and S. aureus was studied. According to the results of bacterial adhesion, PE/GeneO-MPC nanocomposites inhibited the growth of the mass of predominant bacteria. PE/GeneO-MPC could reduce platelet adhesion greatly as compared to PE, which displayed the improved anticoagulant property. The tensile strength and elongation of PE/GeneO-MPC nanocomposites were enhanced by 15.5 and 97.3%, respectively. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013

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